W-18

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H341524

CAS#: 93101-02-1

Description: W-18 is a biochemical.


Chemical Structure

img
W-18
CAS# 93101-02-1

Theoretical Analysis

Hodoodo Cat#: H341524
Name: W-18
CAS#: 93101-02-1
Chemical Formula: C19H20ClN3O4S
Exact Mass: 421.09
Molecular Weight: 421.896
Elemental Analysis: C, 54.09; H, 4.78; Cl, 8.40; N, 9.96; O, 15.17; S, 7.60

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: W-18; W 18; W18.

IUPAC/Chemical Name: (E)-4-Chloro-N-(1-(4-nitrophenethyl)piperidin-2-ylidene)benzenesulfonamide

InChi Key: BKRSVROQVRTSND-XUTLUUPISA-N

InChi Code: InChI=1S/C19H20ClN3O4S/c20-16-6-10-18(11-7-16)28(26,27)21-19-3-1-2-13-22(19)14-12-15-4-8-17(9-5-15)23(24)25/h4-11H,1-3,12-14H2/b21-19+

SMILES Code: O=S(C1=CC=C(Cl)C=C1)(/N=C2N(CCC3=CC=C([N+]([O-])=O)C=C3)CCCC/2)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 421.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Xiong Y, Zhu Z, Guo T, Li H, Xue Q. Synthesis of nanowire bundle-like WO(3)-W(18)O(49) heterostructures for highly sensitive NH(3) sensor application. J Hazard Mater. 2018 Apr 14;353:290-299. doi: 10.1016/j.jhazmat.2018.04.020. [Epub ahead of print] PubMed PMID: 29677531.

2: Champagne AM, Pigg VA, Allen HC, Williams JB. Presence and persistence of a highly ordered lipid phase state in the avian stratum corneum. J Exp Biol. 2018 Mar 28. pii: jeb.176438. doi: 10.1242/jeb.176438. [Epub ahead of print] PubMed PMID: 29593083.

3: Huang XP, Che T, Mangano TJ, Le Rouzic V, Pan YX, Majumdar S, Cameron MD, Baumann MH, Pasternak GW, Roth BL. Fentanyl-related designer drugs W-18 and W-15 lack appreciable opioid activity in vitro and in vivo. JCI Insight. 2017 Nov 16;2(22). pii: 97222. doi: 10.1172/jci.insight.97222. [Epub ahead of print] PubMed PMID: 29202454; PubMed Central PMCID: PMC5752382.

4: Cho JH, Jeong S, Kim EJ, Kim JM, Kim YS, Lee DH. Long-term results of temperature-controlled endobiliary radiofrequency ablation in a normal swine model. Gastrointest Endosc. 2018 Apr;87(4):1147-1150. doi: 10.1016/j.gie.2017.09.013. Epub 2017 Sep 25. PubMed PMID: 28958907.

5: Jiang B, Yuan Y, Zhang X, Feng Z, Liu C. Separation and Enrichment of Lectin from Zihua Snap-Bean (Phaseolus vulgaris) Seeds by PEG 600-Ammonium Sulfate Aqueous Two-Phase System. Molecules. 2017 Sep 22;22(10). pii: E1596. doi: 10.3390/molecules22101596. PubMed PMID: 28937648.

6: Wang HQ, Hu PF, Zheng Y, Zhao Z, Zheng B, Chang J, Wang HJ, Wang JH. Construction of ICG encapsulated W(18)O(49)@MSN as a fluorescence carrier for real-time tracked photothermal therapy. Mater Sci Eng C Mater Biol Appl. 2017 Nov 1;80:102-109. doi: 10.1016/j.msec.2017.05.131. Epub 2017 May 22. PubMed PMID: 28866143.

7: Priyadarshi A, Kumari R, Sharma AK, Jaiswal ML. Preliminary Pharmacognostic and Phytochemical Investigation of Blepharis sindica-T. Anders Seeds. Anc Sci Life. 2016 Oct-Dec;36(2):78-83. doi: 10.4103/asl.ASL_29_16. PubMed PMID: 28446828; PubMed Central PMCID: PMC5382822.

8: McAllister CT, Seville RS, Bursey CR. Helminth (Cestoda, Nematoda) and coccidian (Apicomplexa: Eimeriidae) parasites of the eastern small-footed myotis, Myotis leibii (Chiroptera: Vespertilionidae) from Arkansas, with a description of a new species of Eimeria. Acta Parasitol. 2017 Jun 1;62(2):377-381. doi: 10.1515/ap-2017-0044. PubMed PMID: 28426407; PubMed Central PMCID: PMC5787387.

9: Fujimoto T, Sasaki Y, Wakabayashi H, Sengoku Y, Tsubakimoto S, Nishiyasu T. Maximal workload but not peak oxygen uptake is decreased during immersed incremental exercise at cooler temperatures. Eur J Appl Physiol. 2016 Sep;116(9):1819-27. doi: 10.1007/s00421-016-3438-3. Epub 2016 Jul 25. PubMed PMID: 27456478.

10: Baltisberger JH, Florian P, Keeler EG, Phyo PA, Sanders KJ, Grandinetti PJ. Modifier cation effects on (29)Si nuclear shielding anisotropies in silicate glasses. J Magn Reson. 2016 Jul;268:95-106. doi: 10.1016/j.jmr.2016.05.003. Epub 2016 May 9. PubMed PMID: 27187210.

11: Trinquier A. Fractionation of Oxygen Isotopes by Thermal Ionization Mass Spectrometry Inferred from Simultaneous Measurement of (17)O/(16)O and (18)O/(16)O Ratios and Implications for the (182)Hf-(182)W Systematics. Anal Chem. 2016 Jun 7;88(11):5600-4. doi: 10.1021/acs.analchem.6b01101. Epub 2016 May 10. PubMed PMID: 27157069.

12: Nejm CS Jr, Timi JR, de Araújo WB Jr, Caron FC. Endovenous laser ablation of the great saphenous vein - Varying energy may not affect outcome. Phlebology. 2017 Feb;32(1):13-18. doi: 10.1177/0268355515620944. Epub 2016 Jul 9. PubMed PMID: 26655885.

13: Garrison RW, Von Ellenrieder N. Damselflies of the genus Argia of the Guiana Shield (Odonata: Coenagrionidae). Zootaxa. 2015 Nov 16;4042:1-134. doi: 10.11646/zootaxa.4042.1.1. PubMed PMID: 26624698.

14: Magliery TJ. Protein stability: computation, sequence statistics, and new experimental methods. Curr Opin Struct Biol. 2015 Aug;33:161-8. doi: 10.1016/j.sbi.2015.09.002. Review. PubMed PMID: 26497286; PubMed Central PMCID: PMC4858314.

15: Brown-Xu SE, Chisholm MH, Durr CB, Spilker TF, Young PJ. MM Quadruply Bonded Complexes Supported by Vinylbenzoate Ligands: Synthesis, Characterization, Photophysical Properties and Application as Synthons. Chem Sci. 2015 Mar 1;6(3):1780-1791. Epub 2015 Jan 13. PubMed PMID: 26417424; PubMed Central PMCID: PMC4583209.

16: Iorio ML, Kennedy CD, Huang JI. Limited intercarpal fusion as a salvage procedure for advanced Kienbock disease. Hand (N Y). 2015 Sep;10(3):472-6. doi: 10.1007/s11552-014-9705-z. PubMed PMID: 26330780; PubMed Central PMCID: PMC4551650.

17: Hsu YM, Wang CY, Chang P, Yew TR. Non-stoichiometric W(18)O(49-x)S(x) nanowires for wide spectrum photosensors with high internal gain. Nanoscale. 2015 Jan 21;7(3):901-7. doi: 10.1039/c4nr05234j. PubMed PMID: 25470451.

18: McAllister CT, Seville RS, Duszynski DW, Bush SE. A new species of coccidia (Apicomplexa: Eimeriidae) from Cordillera striped shrew-rat, Chrotomys whiteheadi (Rodentia: Muridae), from the Philippines. Acta Parasitol. 2014 Oct;59(4):686-9. doi: 10.2478/s11686-014-0304-5. Epub 2014 Sep 20. PubMed PMID: 25236280; PubMed Central PMCID: PMC4273579.

19: Zhao P, Xu B, van Leeuwen R, Chen T, Watkins L, Zhou D, Gao P, Xu G, Wang Q, Ghosh C. Compact 4.7 W, 18.3% wall-plug efficiency green laser based on an electrically pumped VECSEL using intracavity frequency doubling. Opt Lett. 2014 Aug 15;39(16):4766-8. doi: 10.1364/OL.39.004766. PubMed PMID: 25121869.

20: Sparks KA, Gleason NJ, Gist R, Langston R, Greathouse DV, Koeppe RE 2nd. Comparisons of interfacial Phe, Tyr, and Trp residues as determinants of orientation and dynamics for GWALP transmembrane peptides. Biochemistry. 2014 Jun 10;53(22):3637-45. doi: 10.1021/bi500439x. Epub 2014 May 29. PubMed PMID: 24829070; PubMed Central PMCID: PMC4053069.