Fentin
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Hodoodo CAT#: H558001

CAS#: 76-87-9

Description: Fentin is an organotin compound (OTC) widely used as an agricultural fungicide and miticide.


Chemical Structure

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Fentin
CAS# 76-87-9

Theoretical Analysis

Hodoodo Cat#: H558001
Name: Fentin
CAS#: 76-87-9
Chemical Formula: C18H16OSn
Exact Mass: 368.02
Molecular Weight: 367.030
Elemental Analysis: C, 58.90; H, 4.39; O, 4.36; Sn, 32.34

Price and Availability

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25g USD 350 2 Weeks
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Synonym: Fentin; AI3-28009; AI3 28009; AI328009; Erithane; Fentine; Tenhide;

IUPAC/Chemical Name: triphenylstannanol

InChi Key: BFWMWWXRWVJXSE-UHFFFAOYSA-M

InChi Code: InChI=1S/3C6H5.H2O.Sn/c3*1-2-4-6-5-3-1;;/h3*1-5H;1H2;/q;;;;+1/p-1

SMILES Code: O[Sn](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 367.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Sarpa M, Tavares Lopes CM, Delgado IF, Paumgartten FJ. Postnatal development and fertility of offspring from mice exposed to triphenyltin (fentin) hydroxide during pregnancy and lactation. J Toxicol Environ Health A. 2010;73(13-14):965-71. doi: 10.1080/15287391003751752. PubMed PMID: 20563930.

2: San Martíns R, Gelmi C, de Oliveira JV, Galo JL, Pranto H. Use of a saponin based molluscicide to control Pomacea canaliculata snails in Southern Brazil. Nat Prod Commun. 2009 Oct;4(10):1327-30. PubMed PMID: 19911565.

3: Li Y, Li B, Liu L, Zhang C, Wu J, Liu Z, Li X. [Simultaneous determination of ten organotin compounds in polyvinyl chloride plastics using gas chromatography-mass spectrometry]. Se Pu. 2009 Jan;27(1):69-73. Chinese. PubMed PMID: 19449544.

4: Henning-de Jong I, van Zelm R, Huijbregts MA, de Zwart D, van der Linden TM, Wintersen A, Posthuma L, van de Meent D. Ranking of agricultural pesticides in the Rhine-Meuse-Scheldt basin based on toxic pressure in marine ecosystems. Environ Toxicol Chem. 2008 Mar;27(3):737-45. PubMed PMID: 17973564.

5: Reddy PS, Pushpalatha T, Reddy PS. Reduction of spermatogenesis and steroidogenesis in mice after fentin and fenbutatin administration. Toxicol Lett. 2006 Sep 30;166(1):53-9. Epub 2006 May 27. PubMed PMID: 16806747.

6: Levin MJ, Gershon AA, Weinberg A, Song LY, Fentin T, Nowak B; Pediatric AIDS Clinical Trials Group 265 Team. Administration of live varicella vaccine to HIV-infected children with current or past significant depression of CD4(+) T cells. J Infect Dis. 2006 Jul 15;194(2):247-55. Epub 2006 Jun 14. PubMed PMID: 16779732.

7: Bastos CS, de Almeida RP, Suinaga FA. Selectivity of pesticides used on cotton (Gossypium hirsutum) to Trichogramma pretiosum reared on two laboratory-reared hosts. Pest Manag Sci. 2006 Jan;62(1):91-8. PubMed PMID: 16308868.

8: Grote K, Niemann L, Gericke C, Selzsam B, Chahoud I. Effects of fentin hydroxide on reproduction of the Japanese quail (Coturnix coturnix japonica). Environ Res. 2006 May;101(1):81-8. Epub 2005 Sep 12. PubMed PMID: 16162336.

9: Ma J. Differential sensitivity of three cyanobacterial and five green algal species to organotins and pyrethroids pesticides. Sci Total Environ. 2005 Apr 1;341(1-3):109-17. Epub 2005 Jan 20. PubMed PMID: 15833245.

10: Ma J, Lin F, Qin W, Wang P. Differential response of four cyanobacterial and green algal species to triazophos, fentin acetate, and ethephon. Bull Environ Contam Toxicol. 2004 Nov;73(5):890-7. PubMed PMID: 15669734.

11: Nagaraju GP, Basha MR, Reddy PS. Organotin-induced hyperglycemia in the crab, Oziotelphusa senex senex Fabricius. Z Naturforsch C. 2001 Mar-Apr;56(3-4):315-7. PubMed PMID: 11371028.

12: Lu FC. A review of the acceptable daily intakes of pesticides assessed by WHO. Regul Toxicol Pharmacol. 1995 Jun;21(3):352-64. Review. PubMed PMID: 7480888.

13: Van Gestel CA, Dirven-Van Breemen EM, Baerselman R, Emans HJ, Janssen JA, Postuma R, Van Vliet PJ. Comparison of sublethal and lethal criteria for nine different chemicals in standardized toxicity tests using the earthworm Eisenia andrei. Ecotoxicol Environ Saf. 1992 Apr;23(2):206-20. PubMed PMID: 1374327.

14: van den Broek HH, Hermes GB, Goewie CE. Determination of fentin residues in potatoes and celery. Analyst. 1988 Aug;113(8):1237-9. PubMed PMID: 3232835.

15: Cotta-Ramusino M, Doci A. Acute toxicity of Brestan and fentin acetate on some freshwater organisms. Bull Environ Contam Toxicol. 1987 Apr;38(4):647-52. PubMed PMID: 3567403.

16: Walker TW, Meek CL, Wright VL, Billodeaux JS. Susceptibility of Romanomermis culicivorax (Nematoda: Mermithidae) postparasites to agrichemicals used in Louisiana rice production. J Am Mosq Control Assoc. 1985 Dec;1(4):477-81. PubMed PMID: 2852708.

17: Baker PG, Farrington DS, Hoodless RA. Fungicide residues. Part VII. Determination of residues of fentin in vegetables and cocoa products by spectrofluorimetry. Analyst. 1980 Mar;105(1248):282-5. PubMed PMID: 7396216.

18: Gaines TB, Kimbrough RD. Toxicity of fentin hydroxide to rats. Toxicol Appl Pharmacol. 1968 May;12(3):397-403. PubMed PMID: 5675476.