WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H591100
CAS#: 55643-87-3
Description: ADD 17014 is an anticonvulsant agent. ADD 17014 is a relatively nontoxic agent that more closely resembles PB and VPA, with a broad and unique spectrum of anticonvulsant activity.
Hodoodo Cat#: H591100
Name: ADD-17014
CAS#: 55643-87-3
Chemical Formula: C13H11ClN4
Exact Mass: 258.07
Molecular Weight: 258.710
Elemental Analysis: C, 60.35; H, 4.29; Cl, 13.70; N, 21.66
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Synonym: ADD-17014; ADD 17014; ADD17014;
IUPAC/Chemical Name: Pyridine, 4-(1-(4-chlorophenyl)-4,5-dihydro-1H-1,2,3-triazol-5-yl)-
InChi Key: VVRREURVTJNTQQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C13H11ClN4/c14-11-1-3-12(4-2-11)18-13(9-16-17-18)10-5-7-15-8-6-10/h1-8,13H,9H2
SMILES Code: ClC1=CC=C(N2N=NCC2C3=CC=NC=C3)C=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 258.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Freeke Hamelijnck MA, Stevenson PJ, Kadaba PK, Damani LA. Triazolines. XXI: Preformulation degradation kinetics and chemical stability of a novel triazoline anticonvulsant. J Pharm Sci. 1992 Apr;81(4):392-6. PubMed PMID: 1501079.
2: Stevenson PJ, Hamelijnck MA, Kadaba PK, Damani LA. Triazolines. XXIII. High-performance liquid chromatographic assay in rat blood for a novel triazoline anticonvulsant (ADD17014). J Chromatogr. 1991 Feb 15;563(2):419-26. PubMed PMID: 2056006.
3: Kadaba PK, Slevin JT. Triazolines XV. Anticonvulsant profile of ADD 17014, a potentially unique 1,2,3-triazoline antiepileptic drug, in mice and rats. Epilepsia. 1988 May-Jun;29(3):330-7. PubMed PMID: 3371287.