Edetol
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    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H591109

CAS#: 102-60-3

Description: Edetol is an ingredient of anti-aging cosmetics; sensitive coating on piezoelectric crystal detectors of SO2.


Chemical Structure

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Edetol
CAS# 102-60-3

Theoretical Analysis

Hodoodo Cat#: H591109
Name: Edetol
CAS#: 102-60-3
Chemical Formula: C14H32N2O4
Exact Mass: 292.24
Molecular Weight: 292.420
Elemental Analysis: C, 57.50; H, 11.03; N, 9.58; O, 21.88

Price and Availability

Size Price Availability Quantity
5g USD 250 2 weeks
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Synonym: Edetol; NSC 369219; NSC-369219; NSC369219

IUPAC/Chemical Name: 1,1',1'',1'''-Ethylenedinitrilotetrapropan-2-ol

InChi Key: NSOXQYCFHDMMGV-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H32N2O4/c1-11(17)7-15(8-12(2)18)5-6-16(9-13(3)19)10-14(4)20/h11-14,17-20H,5-10H2,1-4H3

SMILES Code: CC(O)CN(CC(O)C)CCN(CC(O)C)CC(O)C

Appearance: Liquid

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2922.19.7000

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 292.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Bratlie SO, Casselbrant A, Edebo A, Fändriks L. Support for involvement of the renin-angiotensin system in dysplastic Barrett's esophagus. Scand J Gastroenterol. 2017 Mar;52(3):338-343. doi: 10.1080/00365521.2016.1256423. Epub 2016 Nov 16. PubMed PMID: 27846743.

2: Bratlie SO, Edebo A, Casselbrant A, Helander HF, Fändriks L. The renin-angiotensin system in Barrett's esophagus. Scand J Gastroenterol. 2016 Sep;51(9):1037-42. doi: 10.1080/00365521.2016.1174881. Epub 2016 May 13. PubMed PMID: 27174460.

3: Bratlie SO, Johnsson E, Jönsson C, Fändriks L, Edebo A. Multiple-Band Imaging Provides Better Value Than White-light Endoscopy in Detection of Dysplasia in Patients With Barrett's Esophagus. Clin Gastroenterol Hepatol. 2015 Jun;13(6):1068-74.e2. doi: 10.1016/j.cgh.2014.12.007. Epub 2014 Dec 11. PubMed PMID: 25499989.

4: Elfvin A, Edebo A, Hallersund P, Casselbrant A, Fändriks L. Oxidative and nitrosative stress enzymes in relation to nitrotyrosine in Helicobacter pylori-infected humans. World J Gastrointest Pathophysiol. 2014 Aug 15;5(3):373-9. doi: 10.4291/wjgp.v5.i3.373. PubMed PMID: 25133038; PubMed Central PMCID: PMC4133535.

5: Björkman E, Edebo A, Fändriks L, Casselbrant A. Angiotensin IV and the human esophageal mucosa: An exploratory study in healthy subjects and gastroesophageal reflux disease patients. J Renin Angiotensin Aldosterone Syst. 2015 Sep;16(3):570-7. doi: 10.1177/1470320313512389. Epub 2014 Jan 22. PubMed PMID: 24452037.

6: Björkman EV, Edebo A, Oltean M, Casselbrant A. Esophageal barrier function and tight junction expression in healthy subjects and patients with gastroesophageal reflux disease: functionality of esophageal mucosa exposed to bile salt and trypsin in vitro. Scand J Gastroenterol. 2013 Oct;48(10):1118-26. doi: 10.3109/00365521.2013.828772. PubMed PMID: 24047393.

7: Krarup AL, Gunnarsson J, Brun J, Poulakis A, Edebo A, Ringström G, Drewes AM, Simrén M. Exploration of the effects of gender and mild esophagitis on esophageal pain thresholds in the normal and sensitized state of asymptomatic young volunteers. Neurogastroenterol Motil. 2013 Sep;25(9):766-e580. doi: 10.1111/nmo.12172. Epub 2013 Jul 3. PubMed PMID: 23822673.

8: Björkman E, Edebo A, Casselbrant A, Helander HF, Bratlie SO, Vieth M, Fändriks L. The renin-angiotensin system in the esophageal mucosa of healthy subjects and patients with reflux disease. Scand J Gastroenterol. 2013 Feb;48(2):147-59. doi: 10.3109/00365521.2012.749510. Epub 2012 Dec 28. PubMed PMID: 23270416.

9: Ferreira JA, Lennartsson PR, Edebo L, Taherzadeh MJ. Zygomycetes-based biorefinery: present status and future prospects. Bioresour Technol. 2013 May;135:523-32. doi: 10.1016/j.biortech.2012.09.064. Epub 2012 Sep 27. Review. PubMed PMID: 23127833.

10: Silva FB, Dinis-Ribeiro M, Vieth M, Rabenstein T, Goda K, Kiesslich R, Haringsma J, Edebo A, Toth E, Soares J, Areia M, Lundell L, Marschall HU. Endoscopic assessment and grading of Barrett's esophagus using magnification endoscopy and narrow-band imaging: accuracy and interobserver agreement of different classification systems (with videos). Gastrointest Endosc. 2011 Jan;73(1):7-14. doi: 10.1016/j.gie.2010.09.023. PubMed PMID: 21184868.

11: Zamani A, Edebo L, Niklasson C, Taherzadeh MJ. Temperature shifts for extraction and purification of zygomycetes chitosan with dilute sulfuric acid. Int J Mol Sci. 2010 Aug 13;11(8):2976-87. doi: 10.3390/ijms11082976. PubMed PMID: 21152285; PubMed Central PMCID: PMC2996746.

12: Hallersund P, Helander HF, Casselbrant A, Edebo A, Fändriks L, Elfvin A. Angiotensin II receptor expression and relation to Helicobacter pylori-infection in the stomach of the Mongolian gerbil. BMC Gastroenterol. 2010 Jan 14;10:3. doi: 10.1186/1471-230X-10-3. PubMed PMID: 20074344; PubMed Central PMCID: PMC2823647.

13: Casselbrant A, Edebo A, Hallersund P, Spak E, Helander HF, Jönson C, Fändriks L. Angiotensin II receptors are expressed and functional in human esophageal mucosa. Am J Physiol Gastrointest Liver Physiol. 2009 Nov;297(5):G1019-27. doi: 10.1152/ajpgi.00255.2009. Epub 2009 Sep 24. PubMed PMID: 19779016.

14: Kindlund B, Sjöling A, Hansson M, Edebo A, Hansson LE, Sjövall H, Svennerholm AM, Lundin BS. FOXP3-expressing CD4(+) T-cell numbers increase in areas of duodenal gastric metaplasia and are associated to CD4(+) T-cell aggregates in the duodenum of Helicobacter pylori-infected duodenal ulcer patients. Helicobacter. 2009 Jun;14(3):192-201. doi: 10.1111/j.1523-5378.2009.00673.x. PubMed PMID: 19702849.

15: Lennartsson PR, Karimi K, Edebo L, Taherzadeh MJ. Effects of different growth forms of Mucor indicus on cultivation on dilute-acid lignocellulosic hydrolyzate, inhibitor tolerance, and cell wall composition. J Biotechnol. 2009 Sep 25;143(4):255-61. doi: 10.1016/j.jbiotec.2009.07.011. Epub 2009 Jul 22. PubMed PMID: 19631243.

16: Inci K, Edebo A, Olbe L, Casselbrant A. Expression of protease-activated-receptor 2 (PAR-2) in human esophageal mucosa. Scand J Gastroenterol. 2009;44(6):664-71. doi: 10.1080/00365520902783683. PubMed PMID: 19263271.

17: Kondori N, Edebo L, Mattsby-Baltzer I. A novel monoclonal antibody recognizing beta(1-3) glucans in intact cells of Candida and Cryptococcus. APMIS. 2008 Oct;116(10):867-76. doi: 10.1111/j.1600-0463.2008.01013.x. PubMed PMID: 19132980.

18: Zamani A, Jeihanipour A, Edebo L, Niklasson C, Taherzadeh MJ. Determination of glucosamine and N-acetyl glucosamine in fungal cell walls. J Agric Food Chem. 2008 Sep 24;56(18):8314-8. doi: 10.1021/jf801478j. Epub 2008 Aug 27. PubMed PMID: 18729456.

19: Zamani A, Edebo L, Sjöström B, Taherzadeh MJ. Extraction and precipitation of chitosan from cell wall of zygomycetes fungi by dilute sulfuric acid. Biomacromolecules. 2007 Dec;8(12):3786-90. Epub 2007 Nov 27. PubMed PMID: 18039008.

20: Elfvin A, Edebo A, Bölin I, Fändriks L. Quantitative measurement of nitric oxide and hydrogen peroxide in Helicobacter pylori-infected Mongolian gerbils in vivo. Scand J Gastroenterol. 2007 Oct;42(10):1175-81. PubMed PMID: 17852850.