WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H591266
CAS#: 6508-65-2
Description: Aeruginosin B is a biochemical.
Hodoodo Cat#: H591266
Name: Aeruginosin B
CAS#: 6508-65-2
Chemical Formula: C14H11N3O5S
Exact Mass: 333.04
Molecular Weight: 333.320
Elemental Analysis: C, 50.45; H, 3.33; N, 12.61; O, 24.00; S, 9.62
This product is not in stock, which may be available by custom synthesis.
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Synonym: Aeruginosin B;
IUPAC/Chemical Name: Phenazinium, 7-amino-1-carboxy-5-methyl-3-sulfo-, inner salt
InChi Key: NBUSANFLZHRAMZ-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H11N3O5S/c1-17-11-4-7(15)2-3-10(11)16-13-9(14(18)19)5-8(6-12(13)17)23(20,21)22/h2-6,15H,1H3,(H2,18,19,20,21,22)
SMILES Code: O=S(C1=CC2=C(C(C(O)=O)=C1)N=C3C=CC(N)=CC3=[N+]2C)([O-])=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 333.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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7: Trost BM, Kaneko T, Andersen NG, Tappertzhofen C, Fahr B. Total synthesis of aeruginosin 98B. J Am Chem Soc. 2012 Nov 21;134(46):18944-7. doi: 10.1021/ja309947n. Epub 2012 Nov 12. PubMed PMID: 23116136; PubMed Central PMCID: PMC3551629.
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9: Rounge TB, Rohrlack T, Nederbragt AJ, Kristensen T, Jakobsen KS. A genome-wide analysis of nonribosomal peptide synthetase gene clusters and their peptides in a Planktothrix rubescens strain. BMC Genomics. 2009 Aug 25;10:396. doi: 10.1186/1471-2164-10-396. PubMed PMID: 19706155; PubMed Central PMCID: PMC2739229.
10: Hanessian S, Wang X, Ersmark K, Del Valle JR, Klegraf E. Total synthesis and structural revision of the presumed aeruginosins 205A and B. Org Lett. 2009 Sep 17;11(18):4232-5. doi: 10.1021/ol901702k. Erratum in: Org Lett. 2009 Dec 3;11(23):5566. PubMed PMID: 19691354.
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17: Valls N, Vallribera M, López-Canet M, Bonjoch J. Synthesis of microcin SF608. J Org Chem. 2002 Jul 12;67(14):4945-50. PubMed PMID: 12098309.
18: Valls N, López-Canet M, Vallribera M, Bonjoch J. First total syntheses of aeruginosin 298-A and aeruginosin 298-B, based on a stereocontrolled route to the new amino acid 6-hydroxyoctahydroindole-2-carboxylic acid. Chemistry. 2001 Aug 17;7(16):3446-60. PubMed PMID: 11560314.
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