Carbocysteine
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    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H596464

CAS#: 638-23-3

Description: Carbocysteine is a compound formed when iodoacetic acid reacts with sulfhydryl groups in proteins. It has been used as an anti-infective nasal spray with mucolytic and expectorant action.

Chemical Structure

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Carbocysteine
CAS# 638-23-3
Instruction

Theoretical Analysis

Hodoodo Cat#: H596464
Name: Carbocysteine
CAS#: 638-23-3
Chemical Formula: C5H9NO4S
Exact Mass: 179.03
Molecular Weight: 179.190
Elemental Analysis: C, 33.51; H, 5.06; N, 7.82; O, 35.71; S, 17.89

Price and Availability

Size Price Availability Quantity
5g USD 250
25g USD 450
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Synonym: Carbocysteine; DF 1794Y; Mucofan; PectDrill; Reomucil; Superthiol sirup; NSC 14156; NSC-14156; NSC14156;

IUPAC/Chemical Name: S-(carboxymethyl)-L-cysteine

InChi Key: GBFLZEXEOZUWRN-VKHMYHEASA-N

InChi Code: InChI=1S/C5H9NO4S/c6-3(5(9)10)1-11-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

SMILES Code: N[C@@H](CSCC(O)=O)C(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 179.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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8: Cohen HA, Hoshen M, Gur S, Bahir A, Laks Y, Blau H. Efficacy and tolerability of a polysaccharide-resin-honey based cough syrup as compared to carbocysteine syrup for children with colds: a randomized, single-blinded, multicenter study. World J Pediatr. 2017 Feb;13(1):27-33. doi: 10.1007/s12519-016-0048-4. Epub 2016 Jul 15. PubMed PMID: 27457790.

9: Carrillo L, Sumano H, Medina-Torres L, Tapia G, Gutiérrez L. Rheological study of healthy chicken's pooled tracheobronchial secretions and its modification by mucolytics drugs. Poult Sci. 2016 Nov 1;95(11):2667-2672. Epub 2016 Jul 14. PubMed PMID: 27418656.

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19: Panagopoulos P, Mitchell SC, Steventon GB. S-carboxymethyl-L-cysteine and it (R/S)-S-oxides in beagle dog plasma and hepatic cytosol. Xenobiotica. 2015;45(12):1047-53. doi: 10.3109/00498254.2015.1042538. Epub 2015 Jun 11. PubMed PMID: 26068525.

20: Iino Y, Yoshida N, Kato T, Kakizaki K, Miyazawa T, Kakuta H. Clinical effects of clarithromycin on persistent inflammation following Haemophilus influenzae-positive acute otitis media. Acta Otolaryngol. 2015 Mar;135(3):217-25. doi: 10.3109/00016489.2014.975893. PubMed PMID: 25649881.