WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H596520
CAS#: 139026-54-3
Description: Antho-riamide I is an active peptide from sea anemone Anthopleura elegantissima which inhibits spontaneous contraction of sea anemone muscles.
Hodoodo Cat#: H596520
Name: Antho-riamide I
CAS#: 139026-54-3
Chemical Formula: C30H43N7O6
Exact Mass: 597.33
Molecular Weight: 597.710
Elemental Analysis: C, 60.28; H, 7.25; N, 16.40; O, 16.06
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Synonym: Antho-riamide I;
IUPAC/Chemical Name: (S)-N-((2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl)-5-guanidino-2-((S)-2-((S)-2-hydroxy-3-phenylpropanamido)-3-(4-hydroxyphenyl)propanamido)pentanamide
InChi Key: UBOLUOWRWFHBRN-WCJQXVFBSA-N
InChi Code: InChI=1S/C30H43N7O6/c1-3-18(2)25(26(31)40)37-27(41)22(10-7-15-34-30(32)33)35-28(42)23(16-20-11-13-21(38)14-12-20)36-29(43)24(39)17-19-8-5-4-6-9-19/h4-6,8-9,11-14,18,22-25,38-39H,3,7,10,15-17H2,1-2H3,(H2,31,40)(H,35,42)(H,36,43)(H,37,41)(H4,32,33,34)/t18-,22-,23-,24-,25-/m0/s1
SMILES Code: CC[C@H](C)[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC1=CC=C(O)C=C1)NC([C@@H](O)CC2=CC=CC=C2)=O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 597.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: McFarlane ID, Hudman D, Nothacker HP, Grimmelikhuijzen CJ. The expansion behaviour of sea anemones may be coordinated by two inhibitory neuropeptides, Antho-KAamide and Antho-RIamide. Proc Biol Sci. 1993 Aug 23;253(1337):183-8. PubMed PMID: 8397415.
2: Nothacker HP, Rinehart KL, McFarlane ID, Grimmelikhuijzen CJ. Isolation of two novel neuropeptides from sea anemones: the unusual, biologically active L-3-phenyllactyl-Tyr-Arg-Ile-NH2 and its des-phenyllactyl fragment Tyr-Arg-Ile-NH2. Peptides. 1991 Nov-Dec;12(6):1165-73. PubMed PMID: 1821096.