WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H596811
CAS#: 91921-56-1
Description: Insulin B (20-30) is a peptide hormone produced by beta cells of the pancreatic islets, and it is considered to be the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of, especially glucose from the blood into liver, fat and skeletal muscle cells. In these tissues the absorbed glucose is converted into either glycogen via glycogenesis or fats (triglycerides) via lipogenesis, or, in the case of the liver, into both. Glucose production and secretion by the liver is strongly inhibited by high concentrations of insulin in the blood. Circulating insulin also affects the synthesis of proteins in a wide variety of tissues. It is therefore an anabolic hormone, promoting the conversion of small molecules in the blood into large molecules inside the cells. Low insulin levels in the blood have the opposite effect by promoting widespread catabolism, especially of reserve body fat.
Hodoodo Cat#: H596811
Name: Insulin B (20-30)
CAS#: 91921-56-1
Chemical Formula: C60H85N15O16
Exact Mass: 1,271.63
Molecular Weight: 1,272.420
Elemental Analysis: C, 56.64; H, 6.73; N, 16.51; O, 20.12
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Synonym: Insulin B (20-30); Insulin (B20-B30);
IUPAC/Chemical Name: (2R,3S,6S,9S,12S,18S,21S)-3-((S)-2-(((S)-6-amino-1-(((S)-1-carboxyethyl)amino)-1-oxohexan-2-yl)carbamoyl)pyrrolidine-1-carbonyl)-21-(2-aminoacetamido)-9,12-dibenzyl-18-(3-guanidinopropyl)-2-hydroxy-6-(4-hydroxybenzyl)-5,8,11,14,17,20-hexaoxo-4,7,10,13,16,19-hexaazatetracosan-24-oic acid
InChi Key: MKLPMLKAAHFYJO-AORDDHPWSA-N
InChi Code: InChI=1S/C60H85N15O16/c1-34(59(90)91)67-52(83)41(17-9-10-26-61)71-57(88)46-19-12-28-75(46)58(89)50(35(2)76)74-56(87)45(31-38-20-22-39(77)23-21-38)73-55(86)44(30-37-15-7-4-8-16-37)72-54(85)43(29-36-13-5-3-6-14-36)69-48(79)33-66-51(82)40(18-11-27-65-60(63)64)70-53(84)42(24-25-49(80)81)68-47(78)32-62/h3-8,13-16,20-23,34-35,40-46,50,76-77H,9-12,17-19,24-33,61-62H2,1-2H3,(H,66,82)(H,67,83)(H,68,78)(H,69,79)(H,70,84)(H,71,88)(H,72,85)(H,73,86)(H,74,87)(H,80,81)(H,90,91)(H4,63,64,65)/t34-,35+,40-,41-,42-,43-,44-,45-,46-,50-/m0/s1
SMILES Code: C[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H]1N(C([C@H]([C@H](O)C)NC([C@H](CC2=CC=C(O)C=C2)NC([C@H](CC3=CC=CC=C3)NC([C@H](CC4=CC=CC=C4)NC(CNC([C@H](CCCNC(N)=N)NC([C@H](CCC(O)=O)NC(CN)=O)=O)=O)=O)=O)=O)=O)=O)CCC1)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 1,272.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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