WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H562969
CAS#: 19912-61-9
Description: Furanodiene is an inhibitor of adhesion, migration and invasion of breast cancer cells without inducing cytotoxicity, apoptosis and cell cycle arrest.
Hodoodo Cat#: H562969
Name: Furanodiene
CAS#: 19912-61-9
Chemical Formula: C15H20O
Exact Mass: 216.15
Molecular Weight: 216.320
Elemental Analysis: C, 83.28; H, 9.32; O, 7.40
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Synonym: Furanodiene;
IUPAC/Chemical Name: 3,6,10-Trimethyl-4,7,8,11-tetrahydro-cyclodeca[b]furan
InChi Key: VMDXHYHOJPKFEK-HZAVHUKASA-N
InChi Code: InChI=1S/C15H20O/c1-11-5-4-6-12(2)9-15-14(8-7-11)13(3)10-16-15/h6-7,10H,4-5,8-9H2,1-3H3/b11-7-,12-6+
SMILES Code: C/C(C1)=C\CC/C(C)=C\CC2=C1OC=C2C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 216.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Germano A, Occhipinti A, Barbero F, Maffei ME. A Pilot Study on Bioactive Constituents and Analgesic Effects of MyrLiq®, a Commiphora myrrha Extract with a High Furanodiene Content. Biomed Res Int. 2017;2017:3804356. doi: 10.1155/2017/3804356. Epub 2017 May 24. PubMed PMID: 28626756; PubMed Central PMCID: PMC5463107.
2: Aggarwal BB, Yuan W, Li S, Gupta SC. Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric. Mol Nutr Food Res. 2013 Sep;57(9):1529-42. doi: 10.1002/mnfr.201200838. Epub 2013 Jul 12. Review. PubMed PMID: 23847105.
3: Lu JJ, Dang YY, Huang M, Xu WS, Chen XP, Wang YT. Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae--a review. J Ethnopharmacol. 2012 Sep 28;143(2):406-11. doi: 10.1016/j.jep.2012.07.009. Epub 2012 Jul 20. Review. PubMed PMID: 22820242.