WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H562981
CAS#: 1554271-18-9
Description: Nrf2-Activator-12G is a potent Nrf-2 activator.
Hodoodo Cat#: H562981
Name: Nrf2-Activator-12G
CAS#: 1554271-18-9
Chemical Formula: C15H13ClO3S
Exact Mass: 308.03
Molecular Weight: 308.770
Elemental Analysis: C, 58.35; H, 4.24; Cl, 11.48; O, 15.54; S, 10.38
This product is not in stock, which may be available by custom synthesis.
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Synonym: Nrf2-Activator-12G; Nrf2-Activator-12G; Nrf2-Activator-12G; Nrf2 Activator IV; Nrf2 Activator-IV;
IUPAC/Chemical Name: (E)-1-Chloro-2-(2-(2-methoxyphenylsulfonyl)vinyl)benzene
InChi Key: KVDYSDOWSIXKPB-ZHACJKMWSA-N
InChi Code: InChI=1S/C15H13ClO3S/c1-19-14-8-4-5-9-15(14)20(17,18)11-10-12-6-2-3-7-13(12)16/h2-11H,1H3/b11-10+
SMILES Code: O=S(/C=C/C1=CC=CC=C1Cl)(C2=CC=CC=C2OC)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 308.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Woo SY, Kim JH, Moon MK, Han SH, Yeon SK, Choi JW, Jang BK, Song HJ, Kang YG, Kim JW, Lee J, Kim DJ, Hwang O, Park KD. Discovery of vinyl sulfones as a novel class of neuroprotective agents toward Parkinson's disease therapy. J Med Chem. 2014 Feb 27;57(4):1473-87. doi: 10.1021/jm401788m. Epub 2014 Feb 5. PubMed PMID: 24467268.