WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H591418
CAS#: 18910-65-1 (free base)
Description: Salmefamol is a beta-adrenergic agonist which is used as a stimulant similar to albuterol. It may also be used as a bronchodilator with little effect on the cardiovascular system.
Hodoodo Cat#: H591418
Name: Salmefamol
CAS#: 18910-65-1 (free base)
Chemical Formula: C19H25NO4
Exact Mass: 331.18
Molecular Weight: 331.410
Elemental Analysis: C, 68.86; H, 7.60; N, 4.23; O, 19.31
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Synonym: Salmefamol; AHR 3929; AHR-3929; AHR3929
IUPAC/Chemical Name: 1,3-Benzenedimethanol, 4-hydroxy-alpha(sup 1)-(((2-(4-methoxyphenyl)-1-methylethyl)amino)methyl)-
InChi Key: VPMWDFRZSIMDKW-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H25NO4/c1-13(9-14-3-6-17(24-2)7-4-14)20-11-19(23)15-5-8-18(22)16(10-15)12-21/h3-8,10,13,19-23H,9,11-12H2,1-2H3
SMILES Code: OC(CNC(C)CC1=CC=C(OC)C=C1)C2=CC=C(O)C(CO)=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 331.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Campbell IA, Dash CH, McHardy GJ, Shotter MV. Comparison of salmefamol and salbutamol in patients with chronic airways obstruction. Br J Clin Pharmacol. 1976 Feb;3(1):151-5. PubMed PMID: 788738; PubMed Central PMCID: PMC1428820.
2: Kennedy MC, Posner E, Dash CH. New bronchodilator aerosol, salmefamol, in asthma. Acta Allergol. 1975 Apr;30(1):19-33. PubMed PMID: 1173987.
3: Evans ME, Shenfield GM, Paterson JW. The clinical pharmacology of salmefamol. Br J Clin Pharmacol. 1974 Oct;1(5):391-7. PubMed PMID: 22454916; PubMed Central PMCID: PMC1402468.