AH 7725

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H591423

CAS#: 33459-28-8

Description: AH 7725 inhibits asthma attacks.


Chemical Structure

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AH 7725
CAS# 33459-28-8

Theoretical Analysis

Hodoodo Cat#: H591423
Name: AH 7725
CAS#: 33459-28-8
Chemical Formula: C16H12O6
Exact Mass: 300.06
Molecular Weight: 300.270
Elemental Analysis: C, 64.00; H, 4.03; O, 31.97

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: AH 7725; AH-7725; AH7725;

IUPAC/Chemical Name: 9H-Xanthene-2-carboxylic acid, 7-(2-hydroxyethoxy)-9-oxo-

InChi Key: NADDLRWCPPNNBA-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H12O6/c17-5-6-21-10-2-4-14-12(8-10)15(18)11-7-9(16(19)20)1-3-13(11)22-14/h1-4,7-8,17H,5-6H2,(H,19,20)

SMILES Code: O=C(C1=CC(C2=O)=C(OC3=C2C=C(OCCO)C=C3)C=C1)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 300.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Henning F, Cunninghame CA, Martín MA, Rubio JC, Arenas J, Lucia A, HernáNdez-Laín A, Kohn TA. Muscle fiber type proportion and size is not altered in mcardle disease. Muscle Nerve. 2017 Jun;55(6):916-918. doi: 10.1002/mus.25472. Epub 2016 Dec 16. PubMed PMID: 27859426.

2: Tahmasbpour Marzony E, Ghanei M, Panahi Y. Oxidative stress and altered expression of peroxiredoxin genes family (PRDXS) and sulfiredoxin-1 (SRXN1) in human lung tissue following exposure to sulfur mustard. Exp Lung Res. 2016 May;42(4):217-26. doi: 10.1080/01902148.2016.1194501. Epub 2016 Jun 8. Erratum in: Exp Lung Res. 2016 Jun;42(5):275. PubMed PMID: 27266564.

3: Pontzer H, Brown MH, Raichlen DA, Dunsworth H, Hare B, Walker K, Luke A, Dugas LR, Durazo-Arvizu R, Schoeller D, Plange-Rhule J, Bovet P, Forrester TE, Lambert EV, Thompson ME, Shumaker RW, Ross SR. Metabolic acceleration and the evolution of human brain size and life history. Nature. 2016 May 19;533(7603):390-2. doi: 10.1038/nature17654. Epub 2016 May 4. PubMed PMID: 27144364; PubMed Central PMCID: PMC4942851.

4: Pan GH, Chen Z, Xu L, Zhu JH, Xiang P, Ma JJ, Peng YW, Li GH, Chen XY, Fang JL, Guo YH, Zhang L, Liu LS. Low-dose tacrolimus combined with donor-derived mesenchymal stem cells after renal transplantation: a prospective, non-randomized study. Oncotarget. 2016 Mar 15;7(11):12089-101. doi: 10.18632/oncotarget.7725. PubMed PMID: 26933811; PubMed Central PMCID: PMC4914271.

5: Chang X, Zhang J, Huang C, Pang X, Luo Q, Zhang H, Zhang S. Sex-determining region Y-related high mobility group box (SOX)-2 is overexpressed in cervical squamous cell carcinoma and contributes cervical cancer cell migration and invasion in vitro. Tumour Biol. 2015 Sep;36(10):7725-33. doi: 10.1007/s13277-015-3450-y. Epub 2015 May 3. PubMed PMID: 25935536.

6: Zhang X, Lee SJ, Young MF, Wang MM. The small leucine-rich proteoglycan BGN accumulates in CADASIL and binds to NOTCH3. Transl Stroke Res. 2015 Apr;6(2):148-55. doi: 10.1007/s12975-014-0379-1. Epub 2015 Jan 13. PubMed PMID: 25578324; PubMed Central PMCID: PMC4359085.

7: Zhang X, Lee SJ, Young KZ, Josephson DA, Geschwind MD, Wang MM. Latent NOTCH3 epitopes unmasked in CADASIL and regulated by protein redox state. Brain Res. 2014 Oct 2;1583:230-6. doi: 10.1016/j.brainres.2014.08.018. Epub 2014 Aug 21. PubMed PMID: 25150590; PubMed Central PMCID: PMC4206828.

8: Alvarez-Fischer D, Noelker C, Grünewald A, Vulinović F, Guerreiro S, Fuchs J, Lu L, Lombès A, Hirsch EC, Oertel WH, Michel PP, Hartmann A. Probenecid potentiates MPTP/MPP+ toxicity by interference with cellular energy metabolism. J Neurochem. 2013 Dec;127(6):782-92. doi: 10.1111/jnc.12343. Epub 2013 Jul 8. PubMed PMID: 23802648.

9: Curry JW, Hohl R, Noakes TD, Kohn TA. High oxidative capacity and type IIx fibre content in springbok and fallow deer skeletal muscle suggest fast sprinters with a resistance to fatigue. J Exp Biol. 2012 Nov 15;215(Pt 22):3997-4005. doi: 10.1242/jeb.073684. Epub 2012 Aug 16. PubMed PMID: 22899533; PubMed Central PMCID: PMC3597281.

10: Gaskins GT, Moenter SM. Orexin a suppresses gonadotropin-releasing hormone (GnRH) neuron activity in the mouse. Endocrinology. 2012 Aug;153(8):3850-60. doi: 10.1210/en.2012-1300. Epub 2012 Jun 6. PubMed PMID: 22673226; PubMed Central PMCID: PMC3404355.

11: Wandeler G, Keiser O, Pfeiffer K, Pestilli S, Fritz C, Labhardt ND, Mbofana F, Mudyiradima R, Emmel J, Egger M, Ehmer J; SolidarMed ART program and IeDEA-Southern Africa. Outcomes of antiretroviral treatment programs in rural Southern Africa. J Acquir Immune Defic Syndr. 2012 Feb 1;59(2):e9-16. doi: 10.1097/QAI.0b013e31823edb6a. PubMed PMID: 22067665; PubMed Central PMCID: PMC3259205.

12: Kohn TA, Burroughs R, Hartman MJ, Noakes TD. Fiber type and metabolic characteristics of lion (Panthera leo), caracal (Caracal caracal) and human skeletal muscle. Comp Biochem Physiol A Mol Integr Physiol. 2011 Jun;159(2):125-33. doi: 10.1016/j.cbpa.2011.02.006. Epub 2011 Feb 12. Erratum in: Comp Biochem Physiol A Mol Integr Physiol. 2011 Nov;160(3):445. PubMed PMID: 21320626.

13: Jennings CL, Lambert EV, Collins M, Levitt NS, Goedecke JH. The atypical presentation of the metabolic syndrome components in black African women: the relationship with insulin resistance and the influence of regional adipose tissue distribution. Metabolism. 2009 Feb;58(2):149-57. doi: 10.1016/j.metabol.2008.09.007. PubMed PMID: 19154946.

14: Mukwevho E, Kohn TA, Lang D, Nyatia E, Smith J, Ojuka EO. Caffeine induces hyperacetylation of histones at the MEF2 site on the Glut4 promoter and increases MEF2A binding to the site via a CaMK-dependent mechanism. Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E582-8. doi: 10.1152/ajpendo.00312.2007. Epub 2008 Jan 15. PubMed PMID: 18198354.

15: Wu DM, Wu YN, Guo W, Sameer S. Accuracy of direct digital radiography in the study of the root canal type. Dentomaxillofac Radiol. 2006 Jul;35(4):263-5. PubMed PMID: 16798923.

16: Ikeda K, Brown JA, Yagi T, Norrander JM, Hirono M, Eccleston E, Kamiya R, Linck RW. Rib72, a conserved protein associated with the ribbon compartment of flagellar A-microtubules and potentially involved in the linkage between outer doublet microtubules. J Biol Chem. 2003 Feb 28;278(9):7725-34. Epub 2002 Nov 14. PubMed PMID: 12435737.

17: Kanaev SV, Novikov SN, Leenman EE, Pozharisskiĭ KM. [Comparative analysis of data from trepanobiopsy and radionuclide visualization of bone marrow]. Vopr Onkol. 2001;47(5):566-70. Russian. PubMed PMID: 11785097.

18: Goedecke JH, St Clair Gibson A, Grobler L, Collins M, Noakes TD, Lambert EV. Determinants of the variability in respiratory exchange ratio at rest and during exercise in trained athletes. Am J Physiol Endocrinol Metab. 2000 Dec;279(6):E1325-34. PubMed PMID: 11093921.

19: Ishii M, Horio Y, Tada Y, Hibino H, Inanobe A, Ito M, Yamada M, Gotow T, Uchiyama Y, Kurachi Y. Expression and clustered distribution of an inwardly rectifying potassium channel, KAB-2/Kir4.1, on mammalian retinal Müller cell membrane: their regulation by insulin and laminin signals. J Neurosci. 1997 Oct 15;17(20):7725-35. PubMed PMID: 9315894.

20: Ueki M, Ueda M, Kumagai K, Okamoto Y, Noda S, Matsuoka M. Cervical cytology and conservative management of cervical neoplasias during pregnancy. Int J Gynecol Pathol. 1995 Jan;14(1):63-9. PubMed PMID: 7883428.