SOMG-833 HCl
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Hodoodo CAT#: H563028

CAS#: 1268264-10-3

Description: SOMG-833 HCl is a selective c-MET inhibitor that acts by blocking c-MET dependent neoplastic effects and exerting antitumor activity.


Chemical Structure

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SOMG-833 HCl
CAS# 1268264-10-3

Theoretical Analysis

Hodoodo Cat#: H563028
Name: SOMG-833 HCl
CAS#: 1268264-10-3
Chemical Formula: C22H23ClF3N5O2
Exact Mass: 481.15
Molecular Weight: 481.900
Elemental Analysis: C, 54.83; H, 4.81; Cl, 7.36; F, 11.83; N, 14.53; O, 6.64

Price and Availability

Size Price Availability Quantity
5mg USD 335 2 Weeks
10mg USD 555 2 Weeks
25mg USD 1010 2 Weeks
50mg USD 1600 2 Weeks
100mg USD 2495 2 Weeks
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Synonym: SOMG-833 HCl; SOMG 833 HCl; SOMG833 HCl; SOMG-833 Hydrochloride; SOMG833 Hydrochloride; SOMG 833 Hydrochloride; Zgwatinib Hydrochloride; Zgwatinib HCl;

IUPAC/Chemical Name: [3-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-quinolin-5-yl]-(3-nitro-benzyl)-amine Hydrochloride

InChi Key: GVCODABMZBTSTD-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H22F3N5O2.ClH/c1-28-5-7-29(8-6-28)18-12-19-20(10-16(22(23,24)25)11-21(19)27-14-18)26-13-15-3-2-4-17(9-15)30(31)32;/h2-4,9-12,14,26H,5-8,13H2,1H3;1H

SMILES Code: O=[N+](C1=CC(CNC2=C3C=C(N4CCN(C)CC4)C=NC3=CC(C(F)(F)F)=C2)=CC=C1)[O-].[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 481.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Zhang HT, Wang L, Ai J, Chen Y, He CX, Ji YC, Huang M, Yang JY, Zhang A, Ding J, Geng MY. SOMG-833, a novel selective c-MET inhibitor, blocks c-MET-dependent neoplastic effects and exerts antitumor activity. J Pharmacol Exp Ther. 2014 Jul;350(1):36-45. doi: 10.1124/jpet.114.214817. Epub 2014 Apr 16. PubMed PMID: 24741075.