WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H591635
CAS#: 104-46-1
Description: Anethole is an organic compound that is widely used as a flavoring substance. It is a derivative of phenylpropene, a type of aromatic compound that occurs widely in nature, in essential oils.
Hodoodo Cat#: H591635
Name: Anethole
CAS#: 104-46-1
Chemical Formula: C10H12O
Exact Mass: 148.09
Molecular Weight: 148.210
Elemental Analysis: C, 81.04; H, 8.16; O, 10.80
This product is not in stock, which may be available by custom synthesis.
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Synonym: Anethole; AI3-00380; AI3 00380; AI300380; NSC 4018; NSC-4018; NSC4018
IUPAC/Chemical Name: Anisole, p-propenyl-
InChi Key: RUVINXPYWBROJD-ONEGZZNKSA-N
InChi Code: InChI=1S/C10H12O/c1-3-4-9-5-7-10(11-2)8-6-9/h3-8H,1-2H3/b4-3+
SMILES Code: COC1=CC=C(/C=C/C)C=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 148.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
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2: Sá NAR, Bruno JB, Guerreiro DD, Cadenas J, Alves BG, Cibin FWS, Leal-Cardoso JH, Gastal EL, Figueiredo JR. Anethole reduces oxidative stress and improves in vitro survival and activation of primordial follicles. Braz J Med Biol Res. 2018;51(8):e7129. doi: 10.1590/1414-431x20187129. Epub 2018 May 28. PubMed PMID: 29846431.
3: Cautela D, Vella FM, Castaldo D, Laratta B. Characterization of essential oil recovered from fennel horticultural wastes. Nat Prod Res. 2018 May 30:1-5. doi: 10.1080/14786419.2018.1478827. [Epub ahead of print] PubMed PMID: 29846092.
4: Gomes da Rocha Voris D, Dos Santos Dias L, Alencar Lima J, Dos Santos Cople Lima K, Pereira Lima JB, Dos Santos Lima AL. Evaluation of larvicidal, adulticidal, and anticholinesterase activities of essential oils of Illicium verum Hook. f., Pimenta dioica (L.) Merr., and Myristica fragrans Houtt. against Zika virus vectors. Environ Sci Pollut Res Int. 2018 May 28. doi: 10.1007/s11356-018-2362-y. [Epub ahead of print] PubMed PMID: 29808407.
5: Kang NH, Mukherjee S, Min T, Kang SC, Yun JW. Trans-anethole ameliorates obesity via induction of browning in white adipocytes and activation of brown adipocytes. Biochimie. 2018 May 24. pii: S0300-9084(18)30132-9. doi: 10.1016/j.biochi.2018.05.009. [Epub ahead of print] PubMed PMID: 29803631.
6: Hayashi K, Yamaguchi Y, Ogita A, Tanaka T, Kubo I, Fujita KI. Effect of nagilactone E on cell morphology and glucan biosynthesis in budding yeast Saccharomyces cerevisiae. Fitoterapia. 2018 Jul;128:112-117. doi: 10.1016/j.fitote.2018.05.003. Epub 2018 May 14. PubMed PMID: 29772300.
7: Masoudi S. Volatile Constituents from Different Parts of Three Lamiacea Herbs from Iran. Iran J Pharm Res. 2018 Winter;17(1):365-376. PubMed PMID: 29755567; PubMed Central PMCID: PMC5937106.
8: Zhang G, Yuan C, Sun Y. Effect of Selective Encapsulation of Hydroxypropyl-β-cyclodextrin on Components and Antibacterial Properties of Star Anise Essential Oil. Molecules. 2018 May 9;23(5). pii: E1126. doi: 10.3390/molecules23051126. PubMed PMID: 29747430.
9: Bal S, Yadav A, Verma N, Gupta R, Aggarwal NK. Shielding effect of anethole against arsenic induced genotoxicity in cultured human peripheral blood lymphocytes and effect of GSTO1 polymorphism. 3 Biotech. 2018 May;8(5):232. doi: 10.1007/s13205-018-1263-6. Epub 2018 Apr 30. PubMed PMID: 29725571; PubMed Central PMCID: PMC5928012.
10: Hashem AS, Awadalla SS, Zayed GM, Maggi F, Benelli G. Pimpinella anisum essential oil nanoemulsions against Tribolium castaneum-insecticidal activity and mode of action. Environ Sci Pollut Res Int. 2018 Apr 30. doi: 10.1007/s11356-018-2068-1. [Epub ahead of print] PubMed PMID: 29713977.
11: Sobkowiak R, Bojarska N, Krzyżaniak E, Wągiel K, Ntalli N. Chemoreception of botanical nematicides by Meloidogyne incognita and Caenorhabditis elegans. J Environ Sci Health B. 2018 Apr 30:1-10. doi: 10.1080/03601234.2018.1462936. [Epub ahead of print] PubMed PMID: 29708833.
12: Hançer Aydemir D, Çifçi G, Aviyente V, Boşgelmez-Tinaz G. Quorum sensing inhibitor potential of trans-anethole aganist Pseudomonas aeruginosa. J Appl Microbiol. 2018 Apr 25. doi: 10.1111/jam.13892. [Epub ahead of print] PubMed PMID: 29694695.
13: Wieczyńska J, Cavoski I. Antimicrobial, antioxidant and sensory features of eugenol, carvacrol and trans-anethole in active packaging for organic ready-to-eat iceberg lettuce. Food Chem. 2018 Sep 1;259:251-260. doi: 10.1016/j.foodchem.2018.03.137. Epub 2018 Mar 30. PubMed PMID: 29680052.
14: Kowalcze M, Wyrwa J, Dziubaniuk M, Jakubowska M. Voltammetric Determination of Anethole on La(2)O(3)/CPE and BDDE. J Anal Methods Chem. 2018 Feb 20;2018:2158407. doi: 10.1155/2018/2158407. eCollection 2018. PubMed PMID: 29675284; PubMed Central PMCID: PMC5838461.
15: Burcul F, Blazevic I, Radan M, Politeo O. Terpenes, Phenylpropanoids, Sulfur and Other Essential Oil Constituents as Inhibitors of Cholinesterases. Curr Med Chem. 2018 Mar 29. doi: 10.2174/0929867325666180330092607. [Epub ahead of print] PubMed PMID: 29600750.
16: Seo E, Kang P, Seol GH. Trans-anethole prevents hypertension induced by chronic exposure to both restraint stress and nicotine in rats. Biomed Pharmacother. 2018 Jun;102:249-253. doi: 10.1016/j.biopha.2018.03.081. Epub 2018 Mar 22. PubMed PMID: 29567537.
17: Andrade-Ochoa S, Sánchez-Aldana D, Chacón-Vargas KF, Rivera-Chavira BE, Sánchez-Torres LE, Camacho AD, Nogueda-Torres B, Nevárez-Moorillón GV. Oviposition Deterrent and Larvicidal and Pupaecidal Activity of Seven Essential Oils and their Major Components against Culex quinquefasciatus Say (Diptera: Culicidae): Synergism-antagonism Effects. Insects. 2018 Feb 14;9(1). pii: E25. doi: 10.3390/insects9010025. PubMed PMID: 29443951; PubMed Central PMCID: PMC5872290.
18: Pavela R. Essential oils from Foeniculum vulgare Miller as a safe environmental insecticide against the aphid Myzus persicae Sulzer. Environ Sci Pollut Res Int. 2018 Apr;25(11):10904-10910. doi: 10.1007/s11356-018-1398-3. Epub 2018 Feb 3. PubMed PMID: 29397509.
19: Akhbari M, Kord R, Jafari Nodooshan S, Hamedi S. Analysis and evaluation of the antimicrobial and anticancer activities of the essential oil isolated from Foeniculum vulgare from Hamedan, Iran. Nat Prod Res. 2018 Jan 7:1-4. doi: 10.1080/14786419.2017.1423310. [Epub ahead of print] PubMed PMID: 29308661.
20: Bartoňková I, Dvořák Z. Essential oils of culinary herbs and spices display agonist and antagonist activities at human aryl hydrocarbon receptor AhR. Food Chem Toxicol. 2018 Jan;111:374-384. doi: 10.1016/j.fct.2017.11.049. Epub 2017 Nov 27. PubMed PMID: 29191726.