Palmitic acid
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Hodoodo CAT#: H591740

CAS#: 57-10-3

Description: Palmitic acid, or hexadecanoic acid in IUPAC nomenclature, is the most common saturated fatty acid found in animals, plants and microorganisms.


Chemical Structure

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Palmitic acid
CAS# 57-10-3

Theoretical Analysis

Hodoodo Cat#: H591740
Name: Palmitic acid
CAS#: 57-10-3
Chemical Formula: C16H32O2
Exact Mass: 256.24
Molecular Weight: 256.430
Elemental Analysis: C, 74.94; H, 12.58; O, 12.48

Price and Availability

Size Price Availability Quantity
10g USD 240 2 Weeks
25g USD 400 2 Weeks
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Synonym: Palmitic acid; NSC 5030; NSC-5030; NSC5030

IUPAC/Chemical Name: Hexadecanoic acid

InChi Key: IPCSVZSSVZVIGE-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)

SMILES Code: CCCCCCCCCCCCCCCC(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 256.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Jain A, Mathur A, Pandey U, Sarma HD, Dash A. Synthesis and evaluation of (68)Ga labeled palmitic acid for cardiac metabolic imaging. Appl Radiat Isot. 2018 Jun 5;140:35-40. doi: 10.1016/j.apradiso.2018.06.003. [Epub ahead of print] PubMed PMID: 29936274.

2: Ahmed Z, Malli S, Diaz-Salmeron R, Destruel PL, Da Costa A, Guigner JM, Porcher F, Baptiste B, Ponchel G, Bouchemal K. New insights on the structure of hexagonally faceted platelets from hydrophobically modified chitosan and α-cyclodextrin. Int J Pharm. 2018 Jun 21. pii: S0378-5173(18)30433-2. doi: 10.1016/j.ijpharm.2018.06.035. [Epub ahead of print] PubMed PMID: 29936201.

3: Petropoulos SA, Pereira C, Ntatsi G, Danalatos N, Barros L, Ferreira ICFR. Nutritional value and chemical composition of Greek artichoke genotypes. Food Chem. 2018 Nov 30;267:296-302. doi: 10.1016/j.foodchem.2017.01.159. Epub 2017 Feb 2. PubMed PMID: 29934171.

4: Lucarini M, Durazzo A, Sánchez Del Pulgar J, Gabrielli P, Lombardi-Boccia G. Determination of fatty acid content in meat and meat products: The FTIR-ATR approach. Food Chem. 2018 Nov 30;267:223-230. doi: 10.1016/j.foodchem.2017.11.042. Epub 2017 Nov 11. PubMed PMID: 29934161.

5: Sugawara T, Onoue S, Takimoto H, Kawahara K. Modification of lipid A structure and activity by the introduction of palmitoyltransferase gene to the acyltransferase-knockout mutant of Escherichia coli. Microbiol Immunol. 2018 Jun 22. doi: 10.1111/1348-0421.12631. [Epub ahead of print] PubMed PMID: 29932223.

6: Dogan A, Dalar A, Sadullahoglu C, Battal A, Uzun Y, Celik I, Demirel K. Investigation of the protective effects of horse mushroom (Agaricus arvensis Schaeff.) against carbon tetrachloride-induced oxidative stress in rats. Mol Biol Rep. 2018 Jun 21. doi: 10.1007/s11033-018-4218-4. [Epub ahead of print] PubMed PMID: 29931536.

7: Li XZ, Yan CG, Gao QS, Yan Y, Choi SH, Smith SB. Adipogenic/lipogenic gene expression and fatty acid composition in chuck, loin, and round muscles in response to grain feeding of Yanbian Yellow cattle. J Anim Sci. 2018 Jun 21. doi: 10.1093/jas/sky161. [Epub ahead of print] PubMed PMID: 29931237.

8: Ye JZ, Li YT, Wu WR, Shi D, Fang DQ, Yang LY, Bian XY, Wu JJ, Wang Q, Jiang XW, Peng CG, Ye WC, Xia PC, Li LJ. Dynamic alterations in the gut microbiota and metabolome during the development of methionine-choline-deficient diet-induced nonalcoholic steatohepatitis. World J Gastroenterol. 2018 Jun 21;24(23):2468-2481. doi: 10.3748/wjg.v24.i23.2468. PubMed PMID: 29930468; PubMed Central PMCID: PMC6010937.

9: Das S, Reddy MA, Senapati P, Stapleton K, Lanting L, Wang M, Amaram V, Ganguly R, Zhang L, Devaraj S, Schones DE, Natarajan R. Diabetes Mellitus-Induced Long Noncoding RNA Dnm3os Regulates Macrophage Functions and Inflammation via Nuclear Mechanisms. Arterioscler Thromb Vasc Biol. 2018 Jun 21. pii: ATVBAHA.117.310663. doi: 10.1161/ATVBAHA.117.310663. [Epub ahead of print] PubMed PMID: 29930005.

10: Lacombe RJS, Giuliano V, Chouinard-Watkins R, Bazinet RP. Natural Abundance Carbon Isotopic Analysis Indicates the Equal Contribution of Local Synthesis and Plasma Uptake to Palmitate Levels in the Mouse Brain. Lipids. 2018 Jun 20. doi: 10.1002/lipd.12046. [Epub ahead of print] PubMed PMID: 29923600.

11: Li X, Jin SJ, Su J, Li XX, Xu M. Acid Sphingomyelinase Down-Regulation Alleviates Vascular Endothelial Insulin Resistance in Diabetic Rats. Basic Clin Pharmacol Toxicol. 2018 Jun 19. doi: 10.1111/bcpt.13073. [Epub ahead of print] PubMed PMID: 29923306.

12: Park SH, Kyndt J, Chougule K, Park JJ, Brown JK. Low-phosphate-selected Auxenochlorella protothecoides redirects phosphate to essential pathways while producing more biomass. PLoS One. 2018 Jun 19;13(6):e0198953. doi: 10.1371/journal.pone.0198953. eCollection 2018. PubMed PMID: 29920531; PubMed Central PMCID: PMC6007911.

13: Schiffer JM, Luo M, Dommer AC, Thoron G, Pendergraft MA, Santander MV, Lucero D, Pecora de Barros E, Prather KA, Grassian VH, Amaro RE. Impacts of Lipase Enzyme on the Surface Properties of Marine Aerosols. J Phys Chem Lett. 2018 Jun 19. doi: 10.1021/acs.jpclett.8b01363. [Epub ahead of print] PubMed PMID: 29916254.

14: Ortiz-Rodriguez A, Acaz-Fonseca E, Boya P, Arevalo MA, Garcia-Segura LM. Lipotoxic Effects of Palmitic Acid on Astrocytes Are Associated with Autophagy Impairment. Mol Neurobiol. 2018 Jun 18. doi: 10.1007/s12035-018-1183-9. [Epub ahead of print] PubMed PMID: 29916142.

15: Wu JY, Liao JH, Shieh CJ, Hsieh FC, Liu YC. Kinetic analysis on precursors for iturin A production from Bacillus amyloliquefaciens BPD1. J Biosci Bioeng. 2018 Jun 12. pii: S1389-1723(18)30236-6. doi: 10.1016/j.jbiosc.2018.05.002. [Epub ahead of print] PubMed PMID: 29907529.

16: Ozseyhan ME, Li P, Na G, Li Z, Wang C, Lu C. Improved fatty acid profiles in seeds of Camelina sativa by artificial microRNA mediated FATB gene suppression. Biochem Biophys Res Commun. 2018 Jun 14. pii: S0006-291X(18)31363-9. doi: 10.1016/j.bbrc.2018.06.051. [Epub ahead of print] PubMed PMID: 29906463.

17: Béghin L, Marchandise X, Lien E, Bricout M, Bernet JP, Lienhardt JF, Jeannerot F, Menet V, Requillart JC, Marx J, De Groot N, Jaeger J, Steenhout P, Turck D. Growth, stool consistency and bone mineral content in healthy term infants fed sn-2-palmitate-enriched starter infant formula: A randomized, double-blind, multicentre clinical trial. Clin Nutr. 2018 Jun 1. pii: S0261-5614(18)30200-0. doi: 10.1016/j.clnu.2018.05.015. [Epub ahead of print] PubMed PMID: 29903473.

18: Yang F, Wu J, Zheng Y. [Difference of fatty acids in human milk, bovine milk and powdered formulas with the change of lactation period or suitable object]. Wei Sheng Yan Jiu. 2017 Jul;46(4):579-614. Chinese. PubMed PMID: 29903179.

19: Athanázio-Heliodoro JC, Okino-Delgado CH, Fernandes CJDC, Zanutto MR, Prado DZD, da Silva RA, Facanali R, Zambuzzi WF, Marques MOM, Fleuri LF. Improvement of lipase obtaining system by orange waste-based solid-state fermentation: production, characterization and application. Prep Biochem Biotechnol. 2018 Jun 14:1-9. doi: 10.1080/10826068.2018.1476879. [Epub ahead of print] PubMed PMID: 29902112.

20: Takeda M, Sakaguchi T, Hiraide T, Shibasaki Y, Morita Y, Kikuchi H, Ikegami K, Setou M, Konno H, Takeuchi H. Role of caveolin-1 in hepatocellular carcinoma arising from non-alcoholic fatty liver disease. Cancer Sci. 2018 Jun 13. doi: 10.1111/cas.13659. [Epub ahead of print] PubMed PMID: 29896915.