Septacidin

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H597302

CAS#: 62362-59-8

Description: Septacidin represents a group of l-heptopyranoses containing nucleoside antibiotics with antitumor, antifungal, and pain-relief activities.


Chemical Structure

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Septacidin
CAS# 62362-59-8

Theoretical Analysis

Hodoodo Cat#: H597302
Name: Septacidin
CAS#: 62362-59-8
Chemical Formula: C30H51N7O7
Exact Mass: 621.39
Molecular Weight: 621.380
Elemental Analysis: C, 57.95; H, 8.27; N, 15.77; O, 18.01

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Septacidin; NSC-65104; NSC 65104; NSC65104;

IUPAC/Chemical Name: N-(2-(((2R,3R,4R,5S,6S)-6-((9H-purin-6-yl)amino)-2-((S)-1,2-dihydroxyethyl)-4,5-dihydroxytetrahydro-2H-pyran-3-yl)amino)-2-oxoethyl)-14-methylpentadecanamide

InChi Key: YBZRLMLGUBIIDN-DKOJYIQKSA-N

InChi Code: 1S/C30H51N7O7/c1-19(2)13-11-9-7-5-3-4-6-8-10-12-14-21(40)31-15-22(41)36-23-25(42)26(43)30(44-27(23)20(39)16-38)37-29-24-28(33-17-32-24)34-18-35-29/h17-20,23,25-27,30,38-39,42-43H,3-16H2,1-2H3,(H,31,40)(H,36,41)(H2,32,33,34,35,37)/t20-,23+,25+,26-,27-,30-/m0/s1

SMILES Code: CC(C)CCCCCCCCCCCCC(NCC(N[C@H]1[C@H]([C@@H](O)CO)O[C@H](NC2=C3N=CNC3=NC=N2)[C@@H](O)[C@@H]1O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 621.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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3: Price NP, Furukawa T, Cheng F, Qi J, Chen W, Crich D. Biosynthesis of 4-aminoheptose 2-epimers, core structural components of the septacidins and spicamycins. J Antibiot (Tokyo). 2014 May;67(5):405-14. doi: 10.1038/ja.2014.15. Epub 2014 Mar 19. PubMed PMID: 24643053.

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15: Kamishohara M, Kawai H, Odagawa A, Isoe T, Mochizuki J, Uchida T, Hayakawa Y, Seto H, Tsuruo T, Otake N. Structure-antitumor activity relationship of semi-synthetic spicamycin analogues. J Antibiot (Tokyo). 1993 Sep;46(9):1439-46. PubMed PMID: 8226322.

16: Osda H. [Differentiation inducing compounds]. Tanpakushitsu Kakusan Koso. 1993 Aug;38(11):1791-9. Review. Japanese. PubMed PMID: 8210426.

17: Hayakawa Y, Nakagawa M, Kawai H, Tanabe K, Nakayama H, Shimazu A, Seto H, Otake N. Studies on the differentiation inducers of myeloid leukemic cells. III. Spicamycin, a new inducer of differentiation of HL-60 human promyelocytic leukemia cells. J Antibiot (Tokyo). 1983 Jul;36(7):934-7. PubMed PMID: 6576995.

18: Acton EM, Ryan KJ, Luetzow AE. Antitumor septacidin analogues. J Med Chem. 1977 Nov;20(11):1362-71. PubMed PMID: 915894.

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20: DUTCHER JD, VONSALTZA MH, PANSY FE. SEPTACIDIN, A NEW ANTITUMOR AND ANTIFUNGAL ANTIBIOTIC PRODUCED BY STREPTOMYCES FIBRIATUS. Antimicrob Agents Chemother (Bethesda). 1963;161:83-8. PubMed PMID: 14275007.