BF1

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H563156

CAS#: 163107-37-7

Description: BF1 is a HAT (histone acetyltransferase) inhibitor active both in vitro and in vivo.


Chemical Structure

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BF1
CAS# 163107-37-7

Theoretical Analysis

Hodoodo Cat#: H563156
Name: BF1
CAS#: 163107-37-7
Chemical Formula: C12H12ClN3S
Exact Mass: 265.04
Molecular Weight: 265.750
Elemental Analysis: C, 54.23; H, 4.55; Cl, 13.34; N, 15.81; S, 12.06

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: BF1; BF-1; BF 1;

IUPAC/Chemical Name: 1-(4-(4-Chlorophenyl)thiazol-2-yl)-2-(propan-2-ylidene)hydrazine

InChi Key: WVNNKWMXNNPTIF-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H12ClN3S/c1-8(2)15-16-12-14-11(7-17-12)9-3-5-10(13)6-4-9/h3-7H,1-2H3,(H,14,16)

SMILES Code: C/C(C)=N\NC1=NC(C2=CC=C(Cl)C=C2)=CS1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 265.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Gräf T, Pinto AR. The increasing prevalence of HIV-1 subtype C in Southern Brazil and its dispersion through the continent. Virology. 2013 Jan 5;435(1):170-8. doi: 10.1016/j.virol.2012.08.048. Epub 2012 Sep 20. Review. PubMed PMID: 22999094.

2: Richard D, Picard F. Brown fat biology and thermogenesis. Front Biosci (Landmark Ed). 2011 Jan 1;16:1233-60. Review. PubMed PMID: 21196229.

3: Richard D, Carpentier AC, Doré G, Ouellet V, Picard F. Determinants of brown adipocyte development and thermogenesis. Int J Obes (Lond). 2010 Dec;34 Suppl 2:S59-66. doi: 10.1038/ijo.2010.241. Review. PubMed PMID: 21151149.

4: Hangaishi A, Kurokawa M. Blimp-1 is a tumor suppressor gene in lymphoid malignancies. Int J Hematol. 2010 Jan;91(1):46-53. doi: 10.1007/s12185-009-0472-5. Epub 2010 Jan 5. Review. PubMed PMID: 20047096.

5: Vignais PV, Satre M. Recent developments on structural and functional aspects of the F1 sector of H+-linked ATPases. Mol Cell Biochem. 1984;60(1):33-71. Review. PubMed PMID: 6231469.