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Creatinine
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WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H591968

CAS#: 60-27-5

Description: Creatinine is a Bulking Agent for Freeze Drying.

Chemical Structure

Creatinine

CAS# 60-27-5

Instruction

Theoretical Analysis

Hodoodo Cat#: H591968
Name: Creatinine
CAS#: 60-27-5
Chemical Formula: C4H7N3O
Exact Mass: 113.06
Molecular Weight: 113.120
Elemental Analysis: C, 42.47; H, 6.24; N, 37.15; O, 14.14

Price and Availability

Size	Price	Availability
25g	USD 350	2 Weeks
100g	USD 650	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. Hodoodo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: Creatinine; NSC 13123; NSC-13123; NSC13123

IUPAC/Chemical Name: 2-Imino-1-methylimidazolidin-4-one

InChi Key: DDRJAANPRJIHGJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)

SMILES Code: O=C(CN1C)NC1=N

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 113.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

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Reconstitution Calculator

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Dilution Calculator

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1: Carrier P, Debette-Gratien M, Essig M, Loustaud-Ratti V. Beyond serum creatinine: which tools to evaluate renal function in cirrhotic patients? Hepatol Res. 2018 Jun 28. doi: 10.1111/hepr.13224. [Epub ahead of print] Review. PubMed PMID: 29954046.

2: Zhong LL, Song YQ, Tian XY, Cao H, Ju KJ. Level of uric acid and uric acid/creatinine ratios in correlation with stage of Parkinson disease. Medicine (Baltimore). 2018 Jun;97(26):e10967. doi: 10.1097/MD.0000000000010967. PubMed PMID: 29952939.

3: Guan C, Liang M, Liu R, Qin S, He F, Li J, Zhu X, Dai H, Fu J. Assessment of creatinine and cystatin C-based eGFR equations in Chinese older adults with chronic kidney disease. Int Urol Nephrol. 2018 Jun 13. doi: 10.1007/s11255-018-1909-7. [Epub ahead of print] PubMed PMID: 29948865.

4: den Bakker E, Koene B, van Wijk JAE, Hubeek I, Gemke R, Bökenkamp A. GFR-estimation by serum creatinine during glucocorticosteroid therapy. Clin Exp Nephrol. 2018 Jun 9. doi: 10.1007/s10157-018-1570-6. [Epub ahead of print] PubMed PMID: 29948443.

5: Dziadosz M. Adduct Formation-Supported Two-Way Electrospray Ionization Strategy for the Determination of Urinary Creatinine Concentration with LC-MS-MS in Abstinence Control. J Anal Toxicol. 2018 Jun 26. doi: 10.1093/jat/bky042. [Epub ahead of print] PubMed PMID: 29945182.

6: Kim Y, Cho YS, Kym D, Yoon J, Yim H, Hur J, Chun W. Diagnostic performance of plasma and urine neutrophil gelatinase-associated lipocalin, cystatin C, and creatinine for acute kidney injury in burn patients: A prospective cohort study. PLoS One. 2018 Jun 26;13(6):e0199600. doi: 10.1371/journal.pone.0199600. eCollection 2018. PubMed PMID: 29944687.

7: Farrell MR, Papagiannopoulos D, Ebersole J, White GM, Deane LA. Perinephric fat stranding is associated with elevated creatinine among patients with acutely obstructing ureterolithiasis. J Endourol. 2018 Jun 26. doi: 10.1089/end.2018.0252. [Epub ahead of print] PubMed PMID: 29943669.

8: Moodley N, Hariparshad S, Peer F, Gounden V. Evaluation of the CKD-EPI creatinine based glomerular filtration rate estimating equation in Black African and Indian adults in KwaZulu-Natal, South Africa. Clin Biochem. 2018 Jun 22. pii: S0009-9120(18)30521-6. doi: 10.1016/j.clinbiochem.2018.06.014. [Epub ahead of print] PubMed PMID: 29940141.

9: Omote S, Matsuoka N, Arakawa H, Nakanishi T, Tamai I. Effect of tyrosine kinase inhibitors on renal handling of creatinine by MATE1. Sci Rep. 2018 Jun 18;8(1):9237. doi: 10.1038/s41598-018-27672-y. PubMed PMID: 29915248; PubMed Central PMCID: PMC6006426.

10: Amiri A, Ghanavati R, Riahi Beni H, Sezavar SH, Sheykhvatan M, Arab M. Metabolic Syndrome and the Iodine-Dose/Creatinine Clearance Ratio as Determinants of Contrast-Induced Acute Kidney Injury. Cardiorenal Med. 2018 Jun 15;8(3):217-227. doi: 10.1159/000488374. [Epub ahead of print] PubMed PMID: 29909417.

11: da Silva PM. Putting creatinine and hemoconcentration in their place as prognostic predictors in the conundrum of acute heart failure. Rev Port Cardiol. 2018 Jun 13. pii: S0870-2551(18)30353-6. doi: 10.1016/j.repc.2018.05.011. [Epub ahead of print] English, Portuguese. PubMed PMID: 29908792.

12: Aveitua-Guerrero A, Ballesteros-Angeles L, López-Parra MC, Santos-Barajas R. Correlation and concordance between the primary glomerular filtration MDRD-6 and creatinine clearance by the conventional method. Rev Med Inst Mex Seguro Soc. 2018 Mar-Apr;56(2):148-153. Spanish. PubMed PMID: 29901939.

13: Arase H, Yamada S, Yotsueda R, Taniguchi M, Yoshida H, Tokumoto M, Nakano T, Tsuruya K, Kitazono T. Modified creatinine index and risk for cardiovascular events and all-cause mortality in patients undergoing hemodialysis: The Q-Cohort study. Atherosclerosis. 2018 Jun 2;275:115-123. doi: 10.1016/j.atherosclerosis.2018.06.001. [Epub ahead of print] PubMed PMID: 29890446.

14: Stähli BE, Wischnewsky MB, Jakob P, Klingenberg R, Obeid S, Heg D, Räber L, Windecker S, Roffi M, Mach F, Gencer B, Nanchen D, Jüni P, Landmesser U, Matter CM, Lüscher TF, Maier W. Predictive value of the age, creatinine, and ejection fraction (ACEF) score in patients with acute coronary syndromes. Int J Cardiol. 2018 Jun 1. pii: S0167-5273(18)30997-5. doi: 10.1016/j.ijcard.2018.05.134. [Epub ahead of print] PubMed PMID: 29885826.

15: Życzkowski M, Prokopowicz G, Taborowski P, Nowakowski K, Rajwa P, Stelmach P, Paradysz A. Basic Parameters of Blood Count, Serum Sodium, and Creatinine as Prognostic Factors for Renal Cell Carcinoma at Five-Year Follow-Up. Med Sci Monit. 2018 Jun 9;24:3895-3902. doi: 10.12659/MSM.906867. PubMed PMID: 29885161.

16: Stads S, Schilder L, Nurmohamed SA, Bosch FH, Purmer IM, den Boer SS, Kleppe CG, Vervloet MG, Beishuizen A, Girbes ARJ, Ter Wee PM, Gommers D, Groeneveld ABJ, Oudemans-van Straaten HM; CASH study group. Fluid balance-adjusted creatinine at initiation of continuous venovenous hemofiltration and mortality. A post-hoc analysis of a multicenter randomized controlled trial. PLoS One. 2018 Jun 6;13(6):e0197301. doi: 10.1371/journal.pone.0197301. eCollection 2018. PubMed PMID: 29874271; PubMed Central PMCID: PMC5991340.

17: von Versen-Höynck F, Strauch NK, Liu J, Chi YY, Keller-Woods M, Conrad KP, Baker VL. Effect of Mode of Conception on Maternal Serum Relaxin, Creatinine, and Sodium Concentrations in an Infertile Population. Reprod Sci. 2018 Jan 1:1933719118776792. doi: 10.1177/1933719118776792. [Epub ahead of print] PubMed PMID: 29862889.

18: Jalalonmuhali M, Elagel SMA, Tan MP, Lim SK, Ng KP. Estimating Renal Function in the Elderly Malaysian Patients Attending Medical Outpatient Clinic: A Comparison between Creatinine Based and Cystatin-C Based Equations. Int J Nephrol. 2018 May 13;2018:3081518. doi: 10.1155/2018/3081518. eCollection 2018. PubMed PMID: 29862077; PubMed Central PMCID: PMC5971237.

19: Wijemanne N, Soysa P, Wijesundara S, Perera H. Development and Validation of a Simple High Performance Liquid Chromatography/UV Method for Simultaneous Determination of Urinary Uric Acid, Hypoxanthine, and Creatinine in Human Urine. Int J Anal Chem. 2018 May 15;2018:1647923. doi: 10.1155/2018/1647923. eCollection 2018. PubMed PMID: 29861732; PubMed Central PMCID: PMC5976939.

20: Wang CH, Rubinsky AD, Minichiello T, Shlipak MG, Price EL. Creatinine Versus Cystatin C: Differing Estimates of Renal Function in Hospitalized Veterans Receiving Anticoagulants. J Gen Intern Med. 2018 May 31. doi: 10.1007/s11606-018-4461-3. [Epub ahead of print] PubMed PMID: 29855865.

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Creatinine featured