Albutoin, (S)-

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H597479

CAS#: 52152-25-7

Description: Albutoin, (S)- is a new thiohydantoin derivative for grand mal epilepsies.


Chemical Structure

img
Albutoin, (S)-
CAS# 52152-25-7

Theoretical Analysis

Hodoodo Cat#: H597479
Name: Albutoin, (S)-
CAS#: 52152-25-7
Chemical Formula: C10H16N2OS
Exact Mass: 212.10
Molecular Weight: 212.310
Elemental Analysis: C, 56.57; H, 7.60; N, 13.19; O, 7.54; S, 15.10

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Albutoin, (S)-; L-Leucine-3-allyl-2-thiohydantoin;

IUPAC/Chemical Name: (S)-3-allyl-5-isobutyl-2-thioxoimidazolidin-4-one

InChi Key: RATGSRSDPNECNO-QMMMGPOBSA-N

InChi Code: InChI=1S/C10H16N2OS/c1-4-5-12-9(13)8(6-7(2)3)11-10(12)14/h4,7-8H,1,5-6H2,2-3H3,(H,11,14)/t8-/m0/s1

SMILES Code: O=C([C@H](CC(C)C)N1)N(CC=C)C1=S

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 212.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Green JR, Miller LH, Burnett PD, Ward AA Jr. Clinical evaluation of albutoin. Neurology. 1969 Dec;19(12):1207-11. PubMed PMID: 4901181.

2: Wallin RF, Blackburn WH, Napoli MD. Pharmacologic interactions of albutoin with other anticonvulsant drugs. J Pharmacol Exp Ther. 1970 Aug;174(2):276-82. PubMed PMID: 5451364.

3: Cereghino JJ, Brock JT, Van Meter JC, Penry JK, Smith LD, Fisher P, Ellenberg J. Evaluation of albutoin as an antiepileptic drug. Clin Pharmacol Ther. 1974 Apr;15(4):406-16. PubMed PMID: 4206927.

4: Millichap JG, Ortiz WR. Albutoin, a new thiohydantoin derivative for grand mal epilepsies. Comparison with diphenylhydantoin in a double-blind, controlled study. Neurology. 1967 Feb;17(2):162-5. PubMed PMID: 4959915.