WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H563227
CAS#: 1332879-51-2
Description: Clathrin-IN-1 is a elective clathrin inhibitor. It acts by addressing clathrin function in cell physiology with potential applications as inhibitor of virus and pathogen entry and as modulator of cell signaling.
Hodoodo Cat#: H563227
Name: Clathrin-IN-1
CAS#: 1332879-51-2
Chemical Formula: C19H13N2NaO5S
Exact Mass: 404.04
Molecular Weight: 404.370
Elemental Analysis: C, 56.44; H, 3.24; N, 6.93; Na, 5.69; O, 19.78; S, 7.93
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Synonym: Clathrin-IN-1; Clathrin IN 1; ClathrinIN1; Clathrin-inhibitor-1; Clathrin inhibitor 1
IUPAC/Chemical Name: sodium 2-(4-aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonate
InChi Key: MKPPGLKJTZAXNE-UHFFFAOYSA-M
InChi Code: InChI=1S/C19H14N2O5S.Na/c20-13-6-4-11(5-7-13)10-21-18(22)15-3-1-2-12-8-14(27(24,25)26)9-16(17(12)15)19(21)23;/h1-9H,10,20H2,(H,24,25,26);/q;+1/p-1
SMILES Code: NC1=CC=C(CN2C(C3=CC(S(=O)(O[Na])=O)=CC4=C3C(C2=O)=CC=C4)=O)C=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 404.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Maurange C, Cheng L, Gould AP. Temporal transcription factors and their targets schedule the end of neural proliferation in Drosophila. Cell. 2008 May 30;133(5):891-902. doi: 10.1016/j.cell.2008.03.034. PubMed PMID: 18510932.