WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H597639
CAS#: 32451-23-3 (Li)
Description: L-Mevalonic acid (lithium salt) is a metabolite of the mevalonate pathway, which plays a key role in the biosynthesis of sterols, dolichol, heme and ubiquinone. Of interest for research in the disease areas oncology, autoimmune diseases, artherosclerosis and Alzheimer disease, as well as for inherited deficiencies of mevalonate kinase.
Hodoodo Cat#: H597639
Name: L-Mevalonic acid (lithium salt)
CAS#: 32451-23-3 (Li)
Chemical Formula: C6H11LiO4
Exact Mass: 0.00
Molecular Weight: 154.090
Elemental Analysis: C, 46.77; H, 7.20; Li, 4.50; O, 41.53
Synonym: L-Mevalonic acid; Mevalonic acid, L-; (S)-Mevalonic acid; Lithium (S)-3,5-dihydroxy-3-methyl-valerate; S-MVA-Li
IUPAC/Chemical Name: Lithium (S)-3,5-dihydroxy-3-methyl-pentanoate
InChi Key: PVWNXFFXFNEHDZ-RGMNGODLSA-M
InChi Code: InChI=1S/C6H12O4.Li/c1-6(10,2-3-7)4-5(8)9;/h7,10H,2-4H2,1H3,(H,8,9);/q;+1/p-1/t6-;/m0./s1
SMILES Code: O=C([O-])C[C@@](C)(O)CCO.[Li+]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
| Biological target: | |
| In vitro activity: | |
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The following data is based on the product molecular weight 154.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
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7: Danesh FR, Anel RL, Zeng L, Lomasney J, Sahai A, Kanwar YS. Immunomodulatory effects of HMG-CoA reductase inhibitors. Arch Immunol Ther Exp (Warsz). 2003;51(3):139-48. Review. PubMed PMID: 12894868.
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