WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H597766
CAS#: 4865-85-4
Description: Ochratoxin C is a toxic metabolite from Aspergillus orchraceus.
Hodoodo Cat#: H597766
Name: Ochratoxin C
CAS#: 4865-85-4
Chemical Formula: C22H22ClNO6
Exact Mass: 431.11
Molecular Weight: 431.869
Elemental Analysis: C, 61.19; H, 5.13; Cl, 8.21; N, 3.24; O, 22.23
Synonym: Ochratoxin C; HSDB 3439;
IUPAC/Chemical Name: ethyl ((R)-5-chloro-8-hydroxy-3-methyl-1-oxoisochromane-7-carbonyl)-L-phenylalaninate
InChi Key: BPZZWRPHVVDAPT-PXAZEXFGSA-N
InChi Code: InChI=1S/C22H22ClNO6/c1-3-29-21(27)17(10-13-7-5-4-6-8-13)24-20(26)15-11-16(23)14-9-12(2)30-22(28)18(14)19(15)25/h4-8,11-12,17,25H,3,9-10H2,1-2H3,(H,24,26)/t12-,17+/m1/s1
SMILES Code: O=C(OCC)[C@H](CC1=CC=CC=C1)NC(C2=CC(Cl)=C(C3=C2O)C[C@@H](C)OC3=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 431.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Heussner AH, Bingle LE. Comparative Ochratoxin Toxicity: A Review of the Available Data. Toxins (Basel). 2015 Oct 22;7(10):4253-82. doi: 10.3390/toxins7104253. Review. PubMed PMID: 26506387; PubMed Central PMCID: PMC4626733.
2: Fuchs R, Hult K, Peraica M, Radić B, Plestina R. Conversion of ochratoxin C into ochratoxin A in vivo. Appl Environ Microbiol. 1984 Jul;48(1):41-2. PubMed PMID: 6476830; PubMed Central PMCID: PMC240300.
3: Remiro R, Ibáñez-Vea M, González-Peñas E, Lizarraga E. Validation of a liquid chromatography method for the simultaneous quantification of ochratoxin A and its analogues in red wines. J Chromatogr A. 2010 Dec 24;1217(52):8249-56. doi: 10.1016/j.chroma.2010.11.004. Epub 2010 Nov 9. PubMed PMID: 21111427.
4: Müller G, Burkert B, Möller U, Diller R, Rohrmann B, Rosner H, Köhler H. Ochratoxin A and some of its derivatives modulate radical formation of porcine blood monocytes and granulocytes. Toxicology. 2004 Jul 1;199(2-3):251-9. PubMed PMID: 15147798.
5: Zimmerli B, Dick R. Ochratoxin A in table wine and grape-juice: occurrence and risk assessment. Food Addit Contam. 1996 Aug-Sep;13(6):655-68. PubMed PMID: 8871123.
6: Roth A, Chakor K, Creppy EE, Kane A, Roschenthaler R, Dirheimer G. Evidence for an enterohepatic circulation of ochratoxin A in mice. Toxicology. 1988 Mar;48(3):293-308. PubMed PMID: 3344528.
7: Zhang Y, Wang L, Shen X, Wei X, Huang X, Liu Y, Sun X, Wang Z, Sun Y, Xu Z, Eremin SA, Lei H. Broad-Specificity Immunoassay for Simultaneous Detection of Ochratoxins A, B, and C in Millet and Maize. J Agric Food Chem. 2017 Jun 14;65(23):4830-4838. doi: 10.1021/acs.jafc.7b00770. Epub 2017 Jun 5. PubMed PMID: 28535353.
