WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H592163
CAS#: 28272-18-6
Description: Pyrethrosin is a germacranolide.
Hodoodo Cat#: H592163
Name: Pyrethrosin
CAS#: 28272-18-6
Chemical Formula: C17H22O5
Exact Mass: 306.15
Molecular Weight: 306.360
Elemental Analysis: C, 66.65; H, 7.24; O, 26.11
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Synonym: Pyrethrosin; NSC 22070; NSC-22070; NSC22070
IUPAC/Chemical Name: Germacra-4,11(13)-dien-12-oic acid, 1-beta,10-epoxy-6-alpha,8-alpha-dihydroxy-, 12,8-lactone, acetate, (E)-
InChi Key: JJMLQAVFDJXJAL-JOXWODGISA-N
InChi Code: InChI=1S/C17H22O5/c1-9-5-6-14-17(4,22-14)8-13-15(10(2)16(19)21-13)12(7-9)20-11(3)18/h7,12-15H,2,5-6,8H2,1,3-4H3/b9-7+/t12-,13-,14-,15+,17+/m1/s1
SMILES Code: C/C(CC[C@@H](O1)[C@]1(C)C[C@@]2([H])OC3=O)=C\[C@@H](OC(C)=O)[C@@H]2C3=C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 306.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Mohamed ME, Pahirulzaman KA, Lazarus CM. Production of 3-Oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic Acid in the Fungus Aspergillus oryzae: A Step Towards Heterologous Production of Pyrethrins in Fungi. Mol Biotechnol. 2016 Mar;58(3):172-8. doi: 10.1007/s12033-015-9911-0. PubMed PMID: 26718544.
2: Osimitz TG, Franzosa JA, Maibach HI. Pyrethrins and pyrethrosin content in commercial allergen extracts. Dermatitis. 2009 Nov-Dec;20(6):338-40. PubMed PMID: 19958739.
3: Galal AM. Microbial transformation of pyrethrosin. J Nat Prod. 2001 Aug;64(8):1098-9. PubMed PMID: 11520238.
4: Ward MP, Armstrong RT. Surveys to assess the amount of pesticide in wool and the use of pesticides by woolgrowers in Queensland. Aust Vet J. 2001 May;79(5):358-62. PubMed PMID: 11432004.
5: Schulz KH, Hausen BM, Wallhöfer L, Schmidt-Löffler P. Chrysanthemum allergy. Pt. II: Experimental studies on the causative agents. Arch Dermatol Forsch. 1975;251(3):235-44. German. PubMed PMID: 1090264.
6: Mitchell JC, Dupuis G, Towers GH. Allergic contact dermatitis from pyrethrum (Chrysanthemum spp.). The roles of pyrethrosin, a sesquiterpene lactone, and of pyrethrin II. Br J Dermatol. 1972 Jun;86(6):568-73. PubMed PMID: 5045949.
