Dicyclohexyl ketone
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Hodoodo CAT#: H558459

CAS#: 119-60-8

Description: Dicyclohexyl ketone is a vulcanization accelerator. It is concluded that the No Observed Adverse Effect Levels (NOAELs) for repeat dose and reproductive/developmental toxicity are 100 mg kg-1 day-1.


Chemical Structure

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Dicyclohexyl ketone
CAS# 119-60-8

Theoretical Analysis

Hodoodo Cat#: H558459
Name: Dicyclohexyl ketone
CAS#: 119-60-8
Chemical Formula: C13H22O
Exact Mass: 194.17
Molecular Weight: 194.320
Elemental Analysis: C, 80.35; H, 11.41; O, 8.23

Price and Availability

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25mL USD 350 2 weeks
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Synonym: Dicyclohexyl ketone; Cyclohexane ketone; Ketone, dicyclohexyl;

IUPAC/Chemical Name: Dicyclohexyl ketone

InChi Key: TWXWPPKDQOWNSX-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H22O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h11-12H,1-10H2

SMILES Code: O=C(C1CCCCC1)C2CCCCC2

Appearance: Liquid

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 194.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Ema M, Ito Y, Matsumoto M, Hirose A, Kamata E. Screening study for repeated dose and reproductive/developmental toxicity of rubber accelerator, N,N-dicyclohexyl-2-benzothiazolesulfenamide, in rats. Drug Chem Toxicol. 2007;30(3):167-80. PubMed PMID: 17613004.

2: Kou KG, Longobardi LE, Dong VM. Rhodium(I)-Catalyzed Intermolecular Hydroacylation of α-Keto Amides and Isatins with Non-Chelating Aldehydes. Adv Synth Catal. 2015 Jul 6;357(10):2233-2237. Epub 2015 Jul 14. PubMed PMID: 27134619; PubMed Central PMCID: PMC4847752.

3: Sladowska H. 1,3-dicyclohexyl-5-alkyl-5-aminomethylbarbituric acids as potential antiinflammatory agents. Farmaco Sci. 1977 Dec;32(12):866-71. PubMed PMID: 590495.

4: Castellanos-Blanco N, Arévalo A, García JJ. Nickel-catalyzed transfer hydrogenation of ketones using ethanol as a solvent and a hydrogen donor. Dalton Trans. 2016 Sep 14;45(34):13604-14. doi: 10.1039/c6dt02725c. Epub 2016 Aug 11. PubMed PMID: 27511528.

5: Iwai T, Fujihara T, Terao J, Tsuji Y. Iridium-catalyzed addition of aroyl chlorides and aliphatic acid chlorides to terminal alkynes. J Am Chem Soc. 2012 Jan 18;134(2):1268-74. doi: 10.1021/ja209679c. Epub 2011 Dec 28. PubMed PMID: 22148675.

6: Farahani H, Norouzi P, Dinarvand R, Ganjali MR. Development of dispersive liquid-liquid microextraction combined with gas chromatography-mass spectrometry as a simple, rapid and highly sensitive method for the determination of phthalate esters in water samples. J Chromatogr A. 2007 Nov 23;1172(2):105-12. Epub 2007 Oct 10. PubMed PMID: 17959192.

7: Mirzoeva OK, Yaqoob P, Knox KA, Calder PC. Inhibition of ICE-family cysteine proteases rescues murine lymphocytes from lipoxygenase inhibitor-induced apoptosis. FEBS Lett. 1996 Nov 4;396(2-3):266-70. PubMed PMID: 8915000.