U-99194 maleate
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Hodoodo CAT#: H563410

CAS#: 234757-41-6 (maleate)

Description: U-99194 maleate is a potent, selective D3 antagonist.

Chemical Structure

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U-99194 maleate
CAS# 234757-41-6 (maleate)
Instruction

Theoretical Analysis

Hodoodo Cat#: H563410
Name: U-99194 maleate
CAS#: 234757-41-6 (maleate)
Chemical Formula: C21H31NO6
Exact Mass: 0.00
Molecular Weight: 393.480
Elemental Analysis: C, 64.10; H, 7.94; N, 3.56; O, 24.40

Price and Availability

Size Price Availability Quantity
50mg USD 450 2 Weeks
100mg USD 750 2 Weeks
200mg USD 1350 2 Weeks
500mg USD 2850 2 Weeks
1g USD 4250 2 Weeks
2g USD 6450 2 Weeks
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Related CAS #: 82668-33-5 (free base)   234757-41-6 (maleate)    

Synonym: U-99194 maleate; U 99194 maleate; U99194 maleate; U-99194A; U 99194A; U99194A; U 99194 A; U-99194-A;

IUPAC/Chemical Name: 5,6-Dimethoxy-2-(di-n-propylamino)indan maleate salt

InChi Key: FSIQDESGRQTFNN-BTJKTKAUSA-N

InChi Code: InChI=1S/C17H27NO2.C4H4O4/c1-5-7-18(8-6-2)15-9-13-11-16(19-3)17(20-4)12-14(13)10-15;5-3(6)1-2-4(7)8/h11-12,15H,5-10H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES Code: CCCN(C1CC2=C(C=C(OC)C(OC)=C2)C1)CCC.O=C(O)/C=C\C(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 393.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Hammad H, Wagner JJ. Dopamine-mediated disinhibition in the CA1 region of rat hippocampus via D3 receptor activation. J Pharmacol Exp Ther. 2006 Jan;316(1):113-20. Epub 2005 Sep 14. PubMed PMID: 16162819.

2: Rodríguez-Arias M, Felip CM, Broseta I, Miñarro J. The dopamine D3 antagonist U-99194A maleate increases social behaviors of isolation-induced aggressive male mice. Psychopharmacology (Berl). 1999 May;144(1):90-4. PubMed PMID: 10379629.

3: Manzanedo C, Aguilar MA, Miñarro J. The effects of dopamine D2 and D3 antagonists on spontaneous motor activity and morphine-induced hyperactivity in male mice. Psychopharmacology (Berl). 1999 Mar;143(1):82-8. PubMed PMID: 10227083.