WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H461184
CAS#: 119-41-5
Description: Efloxate is a vasodilator.
Hodoodo Cat#: H461184
Name: Efloxate
CAS#: 119-41-5
Chemical Formula: C19H16O5
Exact Mass: 324.10
Molecular Weight: 324.330
Elemental Analysis: C, 70.36; H, 4.97; O, 24.66
This product is not in stock, which may be available by custom synthesis.
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Synonym: Efloxate; Coril; Angorlisin; Domucor; Flacethyle; RE 1-0185; RE-1-0185; RE1-0185;
IUPAC/Chemical Name: ethyl 2-((4-oxo-2-phenyl-4H-chromen-7-yl)oxy)acetate
InChi Key: ZVXBAHLOGZCFTP-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H16O5/c1-2-22-19(21)12-23-14-8-9-15-16(20)11-17(24-18(15)10-14)13-6-4-3-5-7-13/h3-11H,2,12H2,1H3
SMILES Code: O=c1cc(c2ccccc2)oc3cc(OCC(OCC)=O)ccc31
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 324.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Veronese M, Barzaghi D. [Mutagenesis of efloxate tested in vitro and in vivo]. Boll Chim Farm. 1985 Mar;124(3):124-30. Italian. PubMed PMID: 3896262.
2: Tomasi AM, Masoni A. [Clinical research on the therapeutic efficacy and tolerance of long-acting efloxate in angina pectoris]. Clin Ter. 1977 Aug 15;82(3):227-41. Italian. PubMed PMID: 334448.
3: DEWAR HA, HORLER AR, NEWELL DJ. A clinical trial of penta-erythritol tetranitrate, a khellin derivative (recordil), and iproniazid in angina of effort. Br Heart J. 1959 Jul;21:315-22. PubMed PMID: 13816307; PubMed Central PMCID: PMC1017586.
4: STRAUSAK A, COTTIER P, SCHMID A. [Ethyl-7-hydroxyaceto-flavone (recordil) in the therapy of angina pectoris and its effects on hemodynamics and renal function]. Cardiologia. 1959;34(2):138-46. German. PubMed PMID: 13629509.
5: Tang YZ, Han BJ, Wan BS, Zhou EF, Yang JM. [The effect of 4'-methylrecordil on coronary artery blood flow and experimental myocardial infarction in rabbits]. Yao Xue Xue Bao. 1982 Jul;17(7):487-91. Chinese. PubMed PMID: 7180478.
