WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H598386
CAS#: 23740-25-2
Description: Lanuginosine is an aporphine alkaloid. Lanuginosine exhibited cytotoxicity against U251.
Hodoodo Cat#: H598386
Name: Lanuginosine
CAS#: 23740-25-2
Chemical Formula: C18H11NO4
Exact Mass: 305.07
Molecular Weight: 305.280
Elemental Analysis: C, 70.82; H, 3.63; N, 4.59; O, 20.96
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Synonym: Lanuginosine; NSC 137553; NSC-137553; NSC137553; Oxoxylopin; Oxoxylopine;
IUPAC/Chemical Name: 10-methoxy-8H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinolin-8-one
InChi Key: WLXLLQQGGGHOMA-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H11NO4/c1-21-10-2-3-11-12(7-10)17(20)16-14-9(4-5-19-16)6-13-18(15(11)14)23-8-22-13/h2-7H,8H2,1H3
SMILES Code: O=C1C2=CC(OC)=CC=C2C3=C4OCOC4=CC5=CC=NC1=C53
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 305.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
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7: Lu Z, Zhang Q, Chen R, Yu D. [Aporphine alkaloids from branches and leaves of Polyalthia nemoralis]. Zhongguo Zhong Yao Za Zhi. 2009 Sep;34(18):2343-5. Chinese. PubMed PMID: 20030084.
8: Zhang Z, ElSohly HN, Jacob MR, Pasco DS, Walker LA, Clark AM. New sesquiterpenoids from the root of Guatteria multivenia. J Nat Prod. 2002 Jun;65(6):856-9. PubMed PMID: 12088427.
9: Soni VK, Yadav DK, Bano N, Dixit P, Pathak M, Maurya R, Sahai M, Jain SK, Misra-Bhattacharya S. N-Methyl-6, 7-dimethoxyisoquinolone in Annona squamosa twigs is the major immune modifier to elicit polarized Th1 immune response in BALB/c mice. Fitoterapia. 2012 Jan;83(1):110-6. doi: 10.1016/j.fitote.2011.09.019. Epub 2011 Oct 8. PubMed PMID: 22004725.
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