Acetaldophosphamide

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H592511

CAS#: 113341-60-9

Description: Acetaldophosphamide is a novel stable aldophosphamide analogue and a novel stable aldophosphamide analogue.

Chemical Structure

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Acetaldophosphamide
CAS# 113341-60-9
Instruction

Theoretical Analysis

Hodoodo Cat#: H592511
Name: Acetaldophosphamide
CAS#: 113341-60-9
Chemical Formula: C11H21Cl2N2O6P
Exact Mass: 378.05
Molecular Weight: 379.171
Elemental Analysis: C, 34.84; H, 5.58; Cl, 18.70; N, 7.39; O, 25.32; P, 8.17

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Acetaldophosphamide;

IUPAC/Chemical Name: Phosphorodiamidic acid, N,N-bis(2-chloroethyl)-, 3,3-bis(acetyloxy)propyl ester

InChi Key: QSXPVYOILSESJY-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H21Cl2N2O6P/c1-9(16)20-11(21-10(2)17)3-8-19-22(14,18)15(6-4-12)7-5-13/h11H,3-8H2,1-2H3,(H2,14,18)

SMILES Code: O=P(N(CCCl)CCCl)(N)OCCC(OC(C)=O)OC(C)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 379.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Wang YQ, Farquhar D. Aldophosphamide acetal diacetate and structural analogues: synthesis and cytotoxicity studies. J Med Chem. 1991 Jan;34(1):197-203. PubMed PMID: 1992116.

2: Beran M, Andersson BS, Wang Y, McCredie KB, Farquhar D. The effects of acetaldophosphamide, a novel stable aldophosphamide analogue, on normal human and leukemic progenitor cells in vitro: implications for use in bone marrow purging. Cancer Res. 1988 Jan 15;48(2):339-45. PubMed PMID: 3275495.