WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H598408
CAS#: 2736-23-4
Description: M 12325 is used in the manufacture of furosemide; occupational asthma and rhinitis was observed in workers from a lasamide production line.
Hodoodo Cat#: H598408
Name: M 12325
CAS#: 2736-23-4
Chemical Formula: C7H5Cl2NO4S
Exact Mass: 268.93
Molecular Weight: 270.080
Elemental Analysis: C, 31.13; H, 1.87; Cl, 26.25; N, 5.19; O, 23.70; S, 11.87
Synonym: M 12325; M-12325; M12325; Lasamide;
IUPAC/Chemical Name: 2,4-dichloro-5-sulfamoylbenzoic acid
InChi Key: ZSHHRBYVHTVRFK-UHFFFAOYSA-N
InChi Code: InChI=1S/C7H5Cl2NO4S/c8-4-2-5(9)6(15(10,13)14)1-3(4)7(11)12/h1-2H,(H,11,12)(H2,10,13,14)
SMILES Code: O=C(O)C1=CC(S(=O)(N)=O)=C(Cl)C=C1Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 270.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Ohnishi H, Yamaguchi K, Shimada S, Himuro S, Suzuki Y. Antiviral activity of sodium 5-aminosulfonyl-2,4-dichlorobenzoate (M12325). Antimicrob Agents Chemother. 1982 Aug;22(2):250-4. PubMed PMID: 6927286; PubMed Central PMCID: PMC183720.