Silthiofam
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Hodoodo CAT#: H598434

CAS#: 175217-20-6

Description: Silthiofam is very effective against Ggt, and recently it has been widely used for the control of the plant disease take-all in China. Gaeumannomyces graminis var. tritici (Ggt) causes wheat take-all.

Chemical Structure

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Silthiofam
CAS# 175217-20-6
Instruction

Theoretical Analysis

Hodoodo Cat#: H598434
Name: Silthiofam
CAS#: 175217-20-6
Chemical Formula: C13H21NOSSi
Exact Mass: 267.11
Molecular Weight: 267.460
Elemental Analysis: C, 58.38; H, 7.91; N, 5.24; O, 5.98; S, 11.99; Si, 10.50

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25mg USD 600 4 weeks
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Related CAS #: 175217-20-6  

Synonym: Silthiofam; MON-65500; MON 65500; MON65500; Silthiopham; Latitude;

IUPAC/Chemical Name: N-allyl-4,5-dimethyl-2-(trimethylsilyl)thiophene-3-carboxamide

InChi Key: MXMXHPPIGKYTAR-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H21NOSSi/c1-7-8-14-12(15)11-9(2)10(3)16-13(11)17(4,5)6/h7H,1,8H2,2-6H3,(H,14,15)

SMILES Code: O=C(C1=C([Si](C)(C)C)SC(C)=C1C)NCC=C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 267.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Yun Y, Yu F, Wang N, Chen H, Yin Y, Ma Z. Sensitivity to silthiofam, tebuconazole and difenoconazole of Gaeumannomyces graminis var. tritici isolates from China. Pest Manag Sci. 2012 Aug;68(8):1156-63. doi: 10.1002/ps.3277. Epub 2012 Mar 12. PubMed PMID: 22411909.

2: Chen X, Li Z, Cao Z, Cao X, Chen M. [Determination of six novel amide fungicides in vegetables and fruits by liquid chromatography-tandem mass spectrometry]. Se Pu. 2013 Oct;31(10):954-60. Chinese. PubMed PMID: 24432637.

3: Bailey DJ, Paveley N, Pillinger C, Foulkes J, Spink J, Gilligan CA. Epidemiology and chemical control of take-all on seminal and adventitious roots of wheat. Phytopathology. 2005 Jan;95(1):62-8. doi: 10.1094/PHYTO-95-0062. PubMed PMID: 18943837.

4: Bailey DJ, Paveley N, Spink J, Lucas P, Gilligan CA. Epidemiological analysis of take-all decline in winter wheat. Phytopathology. 2009 Jul;99(7):861-8. doi: 10.1094/PHYTO-99-7-0861. PubMed PMID: 19522584.