• CAT# 530395
  • CAS# 328998-25-0
  • Purity >98%

Price and availability


Structure of 4E1RCat

CAS# 328998-25-0

Size Price Availability Quantity
25 mg$ 150

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$150.00Add to cart

50 mg$ 250

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$250.00Add to cart

100 mg$ 450

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$450.00Add to cart

200 mg$ 750

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$750.00Add to cart

500 mg$ 1550

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$1,550.00Add to cart

Pricing updated 2019-10-08 . Prices are subject to change without notice

4E1RCat is an inhibitor of the eIF4F translation initiation complex that blocks eIF4E:eIF4G and eIF4E:4E-BP1 interactions.

Technical data

IUPAC/Chemnical Name(Z)-4-(3-((5-(4-nitrophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoic acid
Synonym name4E1RCat; eIF4E/eIF4G Interaction Inhibitor II.
Molecule FormlaC28H18N2O6
Molecule Weight 478.46
AppearanceSolid powder
Purity>98% (or refer to the Certificate of Analysis)
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage ConditionDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Stability>2 years if stored properly
Harmonized System (HS) Code 2916.39.79.00
SMILES code O=C1/C(C=C(C2=CC=CC=C2)N1C3=CC=C(C(O)=O)C=C3)=C\C4=CC=C(C5=CC=C([N+]([O-])=O)C=C5)O4
InChi codeInChI=1S/C28H18N2O6/c31-27-21(16-24-14-15-26(36-24)19-6-12-23(13-7-19)30(34)35)17-25(18-4-2-1-3-5-18)29(27)22-10-8-20(9-11-22)28(32)33/h1-17H,(H,32,33)/b21-16-


1: Shuda M, Velásquez C, Cheng E, Cordek DG, Kwun HJ, Chang Y, Moore PS. CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation. Proc Natl Acad Sci U S A. 2015 May 12;112(19):5875-82. doi: 10.1073/pnas.1505787112. PubMed PMID: 25883264; PubMed Central PMCID: PMC4434708. 2: Arnold N, Koppula PR, Gul R, Luck C, Pulakat L. Regulation of cardiac expression of the diabetic marker microRNA miR-29. PLoS One. 2014 Jul 25;9(7):e103284. doi: 10.1371/journal.pone.0103284. PubMed PMID: 25062042; PubMed Central PMCID: PMC4111545.