WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H598490
CAS#: 54935-03-4
Description: Sulisatin is a laxative drug.
Hodoodo Cat#: H598490
Name: Sulisatin
CAS#: 54935-03-4
Chemical Formula: C21H17NO9S2
Exact Mass: 491.03
Molecular Weight: 491.480
Elemental Analysis: C, 51.32; H, 3.49; N, 2.85; O, 29.30; S, 13.05
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Synonym: Sulisatin; DAN 603; DAN-603; DAN603; Laxitex; Sulisatinum;
IUPAC/Chemical Name: (7-methyl-2-oxoindoline-3,3-diyl)bis(4,1-phenylene) bis(hydrogen sulfate)
InChi Key: URNFTLVCQLRCMN-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H17NO9S2/c1-13-3-2-4-18-19(13)22-20(23)21(18,14-5-9-16(10-6-14)30-32(24,25)26)15-7-11-17(12-8-15)31-33(27,28)29/h2-12H,1H3,(H,22,23)(H,24,25,26)(H,27,28,29)
SMILES Code: Cc1c(NC(C2(c3ccc(OS(=O)(O)=O)cc3)c4ccc(OS(=O)(O)=O)cc4)=O)c2ccc1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 491.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Moretó M, Goñalons E, Mylonakis N, Giráldez A, Torralba A. 3,3-Bis-(4-hydroxyphenyl)-7-methyl-2-indolinone (BHMI), the active metabolite of the laxative sulisatin. Arzneimittelforschung. 1979;29(10):1561-4. PubMed PMID: 583222.
2: Moretó M, Goñalons E, Giráldez A, Torralba A. Fate and excretion of sodium sulisatin in the rat. Arch Farmacol Toxicol. 1982 Apr;8(1):21-8. PubMed PMID: 7138083.
3: Moretó M, Goñalons E, Mylonakis N, Giräldez A, Torralba A. Enterohepatic circulation of sodium sulisatin and its effects on glucose absorption in the rat. J Pharm Pharmacol. 1977 Jul;29(7):446-8. PubMed PMID: 19589.