WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H592637
CAS#: 583-03-9
Description: Fenipentol stimulates plasma secretion & exocrine pancreatic secretion.
Hodoodo Cat#: H592637
Name: Fenipentol
CAS#: 583-03-9
Chemical Formula: C11H16O
Exact Mass: 164.12
Molecular Weight: 164.250
Elemental Analysis: C, 80.44; H, 9.82; O, 9.74
Synonym: Fenipentol
IUPAC/Chemical Name: alpha-Butylbenzyl alcohol
InChi Key: OVGORFFCBUIFIA-UHFFFAOYSA-N
InChi Code: InChI=1S/C11H16O/c1-2-3-9-11(12)10-7-5-4-6-8-10/h4-8,11-12H,2-3,9H2,1H3
SMILES Code: CCCCC(O)C1=CC=CC=C1
Appearance: Liquid
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 164.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Fregnan GB, Frigerio L, Porta R, Prada M, Ruggieri F. Therapeutic properties of dihydroxy-dibutylether on sub-acute liver damage induced by several hepatotoxic agents in rats. Int J Tissue React. 1982;4(4):309-18. PubMed PMID: 7169302.
2: Ohe K. [Duodenal ulcer and drug therapy]. Nihon Rinsho. 1984 Jan;42(1):169-77. Review. Japanese. PubMed PMID: 6371307.
3: KOSS FW, BEISENHERZ G, HUBER I, EISELE M. [METABOLISM EXPERIMENTS WITH 1-PHENYL-1-HYDROXY-N-PENTANE]. Arzneimittelforschung. 1964 Mar;14:195-8. German. PubMed PMID: 14235984.
4: KOSS FW, BEISENHERZ G, CHUCHRA U, HUBER I. [THE CHOLERETIC EFFECT OF 1-PHENYL-1-HYDROXY-N-PENTANE]. Arzneimittelforschung. 1964 Mar;14:191-5. German. PubMed PMID: 14235983.
5: ENGELHORN R. [The choleretic effect of 1-phenyl-1-hydroxy-n-pentane]. Arzneimittelforschung. 1960 Apr;10:255-60. German. PubMed PMID: 13820347.
6: Ohki A, Otsuki M, Sakamoto C, Yuu H, Baba S. [Pancreatic exocrine function in rats treated with oral 1-phenyl-1-hydroxy-n-pentane (author's transl)]. Nihon Shokakibyo Gakkai Zasshi. 1982 Mar;79(3):845-50. Japanese. PubMed PMID: 7098123.
7: Endo K, Koizumi M, Kanazawa Y, Yoshida S, Miura M, Kanno T, Koizumi F, Goto Y. Plasma secretin level and exocrine pancreatic secretion in response to intraduodenal infusion of 1-phenyl-1-hydroxy-n-pentane and HCl by using a new four lumen tube. Tohoku J Exp Med. 1980 Aug;131(4):363-71. PubMed PMID: 7466802.
8: DIOGUARDI N, COSTA F, MANNUCCI PM. [Considerations on the cholecystokinetic activity of 1-phenyl-1-hydroxy-N-pentane]. Riforma Med. 1963 May 25;77:561-4. Italian. PubMed PMID: 14027994.
9: Chey WY, Millikan L, Lee KY, Watanabe S, Shiratori K, Takeuchi T. Effect of 1-phenylpentanol on release of secretin and exocrine pancreatic secretion in dogs and humans. Gastroenterology. 1983 Jun;84(6):1578-84. PubMed PMID: 6840488.
10: MUTTI F, CHIARI A. [On the choleretic activity of some derivatives of 1-phenyl-1-hydroxy-n-pentane and 1-phenyl-1-hydroxy-n-hexane]. Boll Chim Farm. 1961 Nov;100:846-50. Italian. PubMed PMID: 14477635.
11: MADULI S. [Experimental study on a new substance with choleretic action: 1-phenyl-1-hydroxy-n-pentane]. Minerva Gastroenterol. 1961 Oct-Dec;7:176-80. Italian. PubMed PMID: 14468143.
12: IOVINO MG, CIARDIELLO A, TORINO L. [ACTION OF 1-PHENYL-1-HYDROXY-N-PENTANE IN THE POST-CHOLECYSTECTOMY SYNDROME (CLINICAL CONTRIBUTION)]. Rass Int Clin Ter. 1965 Apr 30;45:405-11. Italian. PubMed PMID: 14321681.
13: VILLANUEVADIAZ A, BELMONTEVICENTE A, PEREZSANCHEZ C, RODRIGUEZBUJAN L. [ACTION OF 1-PHENYL-1-HYDROXY-N-PENTANE AND 2-(DIMETHYL-N-OCTYLAMMONIUM)-ETHYL BENZILATE BROMIDE ON HEPATIC FUNCTION, STUDIED WITH RADIOACTIVE ROSE BENGAL]. Rev Clin Esp. 1964 Feb 15;92:169-76. Spanish. PubMed PMID: 14151558.
14: VANCINI B. [Clinico-experimental study on a new substance with choleretic action (1-phenyl-1-hydroxy-n-pentane) associated with a spasmolytic having double atropine- and papaverine-like action in patients with hepatobiliary diseases]. Minerva Med. 1962 May 12;53:1478-86. Italian. PubMed PMID: 13924674.
15: Otsuki M, Sakamoto C, Ohki A, Yuu H, Baba S. Effect of intraduodenal instillation of 1-phenyl-1-hydroxy-n-pentane on pancreatic exocrine secretions and immunoreactive secretion release in the rat. Horm Metab Res. 1981 Feb;13(2):80-4. PubMed PMID: 6164622.
16: Otsuki M, Sakamoto C, Ohki A, Yuu H, Maeda M, Baba S. Pancreatic exocrine secretion and immunoreactive secretin release after intraduodenal instillation of 1-phenyl-1-hydroxy-n-pentane and HCl in rats. Dig Dis Sci. 1981 Jun;26(6):538-44. PubMed PMID: 6165534.
