WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H461458
CAS#: 2275-23-2
Description: Vamidothion is a polar organophosphorus pesticide.
Hodoodo Cat#: H461458
Name: Vamidothion
CAS#: 2275-23-2
Chemical Formula: C8H18NO4PS2
Exact Mass: 287.04
Molecular Weight: 287.320
Elemental Analysis: C, 33.44; H, 6.31; N, 4.87; O, 22.27; P, 10.78; S, 22.32
Synonym: Vamidothion; Kilval; Trucidor; RP-9895; RP 9895; RP9895; RP 10465; RP-10465; RP10465;
IUPAC/Chemical Name: O,O-dimethyl S-(2-((1-(methylamino)-1-oxopropan-2-yl)thio)ethyl) phosphorothioate
InChi Key: LESVOLZBIFDZGS-UHFFFAOYSA-N
InChi Code: InChI=1S/C8H18NO4PS2/c1-7(8(10)9-2)15-5-6-16-14(11,12-3)13-4/h7H,5-6H2,1-4H3,(H,9,10)
SMILES Code: CC(SCCSP(OC)(OC)=O)C(NC)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
| Biological target: | |
| In vitro activity: | |
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The following data is based on the product molecular weight 287.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Cabrera HA, Menezes HC, Oliveira JV, Batista RF. Evaluation of residual levels of benomyl, methyl parathion, diuron, and vamidothion in pineapple pulp and bagasse (Smooth cayenne). J Agric Food Chem. 2000 Nov;48(11):5750-3. PubMed PMID: 11087549.
2: Dubosq F, Dedde M. [Determination of vamidothion technical or formulated by gas chromatography]. J Chromatogr. 1972 Sep 20;71(3):557-61. French. PubMed PMID: 5074288.
3: Pak LB. [The toxicity of Vamidothion in relation to warm-blooded animals]. Gig Tr Prof Zabol. 1970 Feb;14(2):58-9. Russian. PubMed PMID: 5443457.
4: Hayama T, Yoshida H, Todoroki K, Nohta H, Yamaguchi M. Determination of polar organophosphorus pesticides in water samples by hydrophilic interaction liquid chromatography with tandem mass spectrometry. Rapid Commun Mass Spectrom. 2008 Jul;22(14):2203-10. doi: 10.1002/rcm.3573. PubMed PMID: 18543372.
5: Shirasu Y, Moriya M, Kato K, Furuhashi A, Kada T. Mutagenicity screening of pesticides in the microbial system. Mutat Res. 1976 Jan;40(1):19-30. PubMed PMID: 814455.
6: Ingelse BA, van Dam RC, Vreeken RJ, Mol HG, Steijger OM. Determination of polar organophosphorus pesticides in aqueous samples by direct injection using liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2001 May 18;918(1):67-78. PubMed PMID: 11403457.
7: Tezuka H, Ando N, Suzuki R, Terahata M, Moriya M, Shirasu Y. Sister-chromatid exchanges and chromosomal aberrations in cultured Chinese hamster cells treated with pesticides positive in microbial reversion assays. Mutat Res. 1980 Jun;78(2):177-91. PubMed PMID: 7393245.
8: Mol HG, van Dam RC, Steijger OM. Determination of polar organophosphorus pesticides in vegetables and fruits using liquid chromatography with tandem mass spectrometry: selection of extraction solvent. J Chromatogr A. 2003 Oct 10;1015(1-2):119-27. PubMed PMID: 14570325.
9: Abe T, Yoshiike N, Yamaguchi H. [Utilization of school lunch dietary data to estimate theoretical maximum daily intake (TMDI) of selected pesticide residues]. Nihon Eiseigaku Zasshi. 2003 Sep;58(3):376-84. Japanese. PubMed PMID: 14533567.
10: Gru Y, Colin R, Le Cloirec P. Investigation of matrix effects for some pesticides in waters by on-line solid-phase extraction-liquid chromatography coupled with triple quadrupole linear ion-trap mass spectrometry and the use of postcolumn introduction. J AOAC Int. 2010 May-Jun;93(3):1020-31. PubMed PMID: 20629409.
11: Drevenkar V, Radić Z, Vasilić Z, Reiner E. Dialkylphosphorus metabolites in the urine and activities of esterases in the serum as biochemical indices for human absorption of organophosphorus pesticides. Arch Environ Contam Toxicol. 1991 Apr;20(3):417-22. PubMed PMID: 1650168.
