WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H598831
CAS#: 325144-67-0
Description: Licoagrochalcone B is a flavonoid extracted from Patrinia villosa.
Hodoodo Cat#: H598831
Name: Licoagrochalcone B
CAS#: 325144-67-0
Chemical Formula: C21H20O4
Exact Mass: 336.14
Molecular Weight: 336.380
Elemental Analysis: C, 74.98; H, 5.99; O, 19.02
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: Licoagrochalcone B;
IUPAC/Chemical Name: (E)-1-(4-hydroxyphenyl)-3-(5-methoxy-2,2-dimethyl-2H-chromen-6-yl)prop-2-en-1-one
InChi Key: BOJUBZPEDAAMPG-UXBLZVDNSA-N
InChi Code: InChI=1S/C21H20O4/c1-21(2)13-12-17-19(25-21)11-7-15(20(17)24-3)6-10-18(23)14-4-8-16(22)9-5-14/h4-13,22H,1-3H3/b10-6+
SMILES Code: O=C(C1=CC=C(O)C=C1)/C=C/C2=CC=C3C(C=CC(C)(C)O3)=C2OC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 336.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Peng J, Fan G, Chai Y, Wu Y. Efficient new method for extraction and isolation of three flavonoids from Patrinia villosa Juss. by supercritical fluid extraction and high-speed counter-current chromatography. J Chromatogr A. 2006 Jan 13;1102(1-2):44-50. Epub 2005 Nov 8. PubMed PMID: 16288764.
2: Peng J, Fan G, Wu Y. Preparative isolation of four new and two known flavonoids from the leaf of Patrinia villosa Juss. by counter-current chromatography and evaluation of their anticancer activities in vitro. J Chromatogr A. 2006 May 19;1115(1-2):103-11. Epub 2006 Mar 20. PubMed PMID: 16545824.
3: Lin Y, Kuang Y, Li K, Wang S, Song W, Qiao X, Sabir G, Ye M. Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. Bioorg Med Chem. 2017 Jul 15;25(14):3706-3713. doi: 10.1016/j.bmc.2017.05.009. Epub 2017 May 6. PubMed PMID: 28522265.
4: Kuang Y, Lin Y, Li K, Song W, Ji S, Qiao X, Zhang Q, Ye M. Screening of hepatoprotective compounds from licorice against carbon tetrachloride and acetaminophen induced HepG2 cells injury. Phytomedicine. 2017 Oct 15;34:59-66. doi: 10.1016/j.phymed.2017.08.005. Epub 2017 Aug 7. PubMed PMID: 28899510.
5: Adem FA, Kuete V, Mbaveng AT, Heydenreich M, Ndakala A, Irungu B, Efferth T, Yenesew A. Cytotoxic benzylbenzofuran derivatives from Dorstenia kameruniana. Fitoterapia. 2018 Jul;128:26-30. doi: 10.1016/j.fitote.2018.04.019. Epub 2018 Apr 30. PubMed PMID: 29715541.