WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H461621
CAS#: 151489-04-2
Description: S 16317 is a dihydropyridine derivatives with low calcium channel affinity.
Hodoodo Cat#: H461621
Name: S 16317
CAS#: 151489-04-2
Chemical Formula: C28H33Cl2N3O6
Exact Mass: 577.17
Molecular Weight: 578.480
Elemental Analysis: C, 58.14; H, 5.75; Cl, 12.26; N, 7.26; O, 16.59
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Synonym: S 16317; S-16317; S16317;
IUPAC/Chemical Name: 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-6-methyl-2-((2-(2-((pyridin-4-ylmethyl)amino)ethoxy)ethoxy)methyl)-1,4-dihydropyridine-3,5-dicarboxylate
InChi Key: ACRICECUZJTXPQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C28H33Cl2N3O6/c1-4-39-28(35)25-22(17-38-15-14-37-13-12-32-16-19-8-10-31-11-9-19)33-18(2)23(27(34)36-3)24(25)20-6-5-7-21(29)26(20)30/h5-11,24,32-33H,4,12-17H2,1-3H3
SMILES Code: O=C(C1=C(C)NC(COCCOCCNCC2=CC=NC=C2)=C(C(OCC)=O)C1C3=CC=CC(Cl)=C3Cl)OC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 578.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Kraus-Berthier L, Guilbaud N, Peglion JL, Leonce S, Lombet A, Pierre A, Atassi G. In vivo reversal of multidrug resistance by two new dihydropyridine derivatives, S16317 and S16324. Acta Oncol. 1994;33(6):631-7. PubMed PMID: 7946440.