Quinfamide

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H592793

CAS#: 62265-68-3

Description: Quinfamide is used in the treatment of chronic amebiasis in pediatric patients.


Chemical Structure

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Quinfamide
CAS# 62265-68-3

Theoretical Analysis

Hodoodo Cat#: H592793
Name: Quinfamide
CAS#: 62265-68-3
Chemical Formula: C16H13Cl2NO4
Exact Mass: 353.02
Molecular Weight: 354.180
Elemental Analysis: C, 54.26; H, 3.70; Cl, 20.02; N, 3.95; O, 18.07

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Quinfamide; Quinfamido

IUPAC/Chemical Name: 2-Furancarboxylic acid, 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester

InChi Key: SBJGFIXQRZOVTO-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H13Cl2NO4/c17-14(18)15(20)19-7-1-3-10-9-11(5-6-12(10)19)23-16(21)13-4-2-8-22-13/h2,4-6,8-9,14H,1,3,7H2

SMILES Code: O=C(C1=CC=CO1)OC2=CC3=C(N(C(C(Cl)Cl)=O)CCC3)C=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 354.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Naguib IA, Hassan ES, Emam AA, Abdelaleem EA. Development and Validation of HPTLC and Green HPLC Methods for Determination of a New Combination of Quinfamide and Mebendazole. J Chromatogr Sci. 2019 Dec 19;58(1):16-21. doi:10.1093/chromsci/bmz100. PMID: 31879753.
2. Cedillo-Rivera R, Muñoz O. In-vitro susceptibility of Giardia lamblia to albendazole, mebendazole and other chemotherapeutic agents. J Med Microbiol. 1992 Sep;37(3):221-4. doi: 10.1099/00222615-37-3-221. PMID: 1518040.
3. Padilla N, Diaz R, Alarcon A, Barreda R. Antiamoebic chemoprophylaxis using quinfamide in children: a comparative study. ScientificWorldJournal. 2002 Apr 20;2:1070-8. doi: 10.1100/tsw.2002.174. PMID: 12805964; PMCID: PMC6009339.
4. Padilla N, Díaz R, Muñoz M. Efficacy and Safety of Quinfamide versus Secnidazole in the Management of Amoebic NonDysenteric Colitis in Children. Clin Drug Investig. 2000;20(2):89-93. doi: 10.2165/00044011-200020020-00003. PMID:
23315350.