WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H572369
CAS#: 2135330-58-2
Description: Pyrene-PEG2-azide is a pyrene labeled PEG derivative containing an azide group which enables Click Chemistry labeling with any alkyne-bearing molecules and thus turns any molecule into pyrene-bearing probe. The hydrophilic PEG linker can increase solubility and facilitate attachment to biomolecules in aqueous solutions.
Hodoodo Cat#: H572369
Name: Pyrene-PEG2-azide
CAS#: 2135330-58-2
Chemical Formula: C23H22N4O3
Exact Mass: 402.17
Molecular Weight: 402.450
Elemental Analysis: C, 68.64; H, 5.51; N, 13.92; O, 11.93
Synonym: Pyrene-PEG2-azide
IUPAC/Chemical Name: N-(2-(2-(2-azidoethoxy)ethoxy)ethyl)pyrene-1-carboxamide
InChi Key: CXNRBKHYGKLDHH-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H22N4O3/c24-27-26-11-13-30-15-14-29-12-10-25-23(28)20-9-7-18-5-4-16-2-1-3-17-6-8-19(20)22(18)21(16)17/h1-9H,10-15H2,(H,25,28)
SMILES Code: O=C(NCCOCCOCCN=[N+]=[N-])C1=CC=C(C=C2)C3=C1C=CC4=C3C2=CC=C4
Appearance: Solid powder
Purity: >96% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, DMF, DCM
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info: Solubility: DMSO, DMF, DCM Excitation maximum (nm): 343; 326; 313 Emission maximum (nm): 377; 397
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 402.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
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3: Ruan S, Qian J, Shen S, Chen J, Zhu J, Jiang X, He Q, Yang W, Gao H. Fluorescent carbonaceous nanodots for noninvasive glioma imaging after angiopep-2 decoration. Bioconjug Chem. 2014 Dec 17;25(12):2252-9. doi: 10.1021/bc500474p. Epub 2014 Nov 11. PubMed PMID: 25387274.
4: Ruan S, Wan J, Fu Y, Han K, Li X, Chen J, Zhang Q, Shen S, He Q, Gao H. PEGylated fluorescent carbon nanoparticles for noninvasive heart imaging. Bioconjug Chem. 2014 Jun 18;25(6):1061-8. doi: 10.1021/bc5001627. Epub 2014 May 22. PubMed PMID: 24852402.
5: Paira TK, Saha A, Banerjee S, Das T, Das P, Jana NR, Mandal TK. Fluorescent amphiphilic PEG-peptide-PEG triblock conjugate micelles for cell imaging. Macromol Biosci. 2014 Jul;14(7):929-35. doi: 10.1002/mabi.201400083. Epub 2014 Mar 31. PubMed PMID: 24687698.
6: Okuda T, Kobayashi Y, Yanamoto S, Okamoto H. PEG conjugation of a near-infrared fluorescent probe for noninvasive dual imaging of lung deposition and gene expression by pulmonary gene delivery. J Drug Target. 2012 Nov;20(9):801-12. doi: 10.3109/1061186X.2012.722639. Epub 2012 Sep 26. PubMed PMID: 23009266.