Quinalphos
featured

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H461752

CAS#: 13593-03-8

Description: Quinalphos is an organic thiophosphate and an organothiophosphate insecticide.

Chemical Structure

img
Quinalphos
CAS# 13593-03-8
Instruction

Theoretical Analysis

Hodoodo Cat#: H461752
Name: Quinalphos
CAS#: 13593-03-8
Chemical Formula: C12H15N2O3PS
Exact Mass: 298.05
Molecular Weight: 298.297
Elemental Analysis: C, 48.32; H, 5.07; N, 9.39; O, 16.09; P, 10.38; S, 10.75

Price and Availability

Size Price Availability Quantity
100mg USD 220 2 Weeks
Bulk inquiry

Synonym: Quinalphos; Chinalphos; Diethquinalphion; Ekalux; Quinaltaf; S-6538; S 6538; S6538; Savall;

IUPAC/Chemical Name: O,O-diethyl O-(quinoxalin-2-yl) phosphorothioate

InChi Key: JYQUHIFYBATCCY-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H15N2O3PS/c1-3-15-18(19,16-4-2)17-12-9-13-10-7-5-6-8-11(10)14-12/h5-9H,3-4H2,1-2H3

SMILES Code: S=P(OCC)(OC1=NC2=CC=CC=C2N=C1)OCC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 298.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Talwar MP, Mulla SI, Ninnekar HZ. Biodegradation of organophosphate pesticide quinalphos by Ochrobactrum sp. strain HZM. J Appl Microbiol. 2014 Nov;117(5):1283-92. doi: 10.1111/jam.12627. Epub 2014 Oct 3. PubMed PMID: 25155583.

2: Dhanjal NI, Kaur P, Sud D, Cameotra SS. Persistence and biodegradation of quinalphos using soil microbes. Water Environ Res. 2014 May;86(5):457-61. PubMed PMID: 24961072.

3: Yang L, Han J, Liu W, Li J, Jiang L. Conversion of inhibition biosensing to substrate-like biosensing for quinalphos selective detection. Anal Chem. 2015 May 19;87(10):5270-7. doi: 10.1021/acs.analchem.5b00376. Epub 2015 May 7. PubMed PMID: 25921798.

4: Muttappa K, Reddy HR, Rajesh M, Padmanabha A. Quinalphos induced alteration in respiratory rate and food consumption of freshwater fish Cyprinus carpio. J Environ Biol. 2014 Mar;35(2):395-8. PubMed PMID: 24665768.

5: Hemalatha D, Amala A, Rangasamy B, Nataraj B, Ramesh M. Sublethal toxicity of quinalphos on oxidative stress and antioxidant responses in a freshwater fish Cyprinus carpio. Environ Toxicol. 2016 Nov;31(11):1399-1406. doi: 10.1002/tox.22145. Epub 2015 Apr 21. PubMed PMID: 25899319.

6: Subramaneyaan M, Jain S, Yadav C, Arora VK, Banerjee BD, Ahmed RS. Quinalphos induced oxidative stress and histoarcheitectural alterations in adult male albino rats. Environ Toxicol Pharmacol. 2012 Nov;34(3):673-8. doi: 10.1016/j.etap.2012.10.003. Epub 2012 Oct 18. PubMed PMID: 23146591.

7: Mohapatra S, Deepa M. Persistence and dissipation of quinalphos in/on cauliflower and soil under the semi arid climatic conditions of Karnataka, India. Bull Environ Contam Toxicol. 2013 Apr;90(4):489-93. doi: 10.1007/s00128-012-0937-8. Epub 2013 Jan 5. PubMed PMID: 23292486.

8: Kokilavani P, Suriyakalaa U, Elumalai P, Abirami B, Ramachandran R, Sankarganesh A, Achiraman S. Antioxidant mediated ameliorative steroidogenesis by Commelina benghalensis L. and Cissus quadrangularis L. against quinalphos induced male reproductive toxicity. Pestic Biochem Physiol. 2014 Feb;109:18-33. doi: 10.1016/j.pestbp.2014.01.002. Epub 2014 Jan 24. PubMed PMID: 24581381.

9: Gupta B, Rani M, Salunke R, Kumar R. In vitro and in vivo studies on degradation of quinalphos in rats. J Hazard Mater. 2012 Apr 30;213-214:285-91. doi: 10.1016/j.jhazmat.2012.01.089. Epub 2012 Feb 6. PubMed PMID: 22356742.

10: Viswanathan S. Unusual complications of quinalphos poisoning. Case Rep Emerg Med. 2013;2013:809174. doi: 10.1155/2013/809174. Epub 2013 May 12. PubMed PMID: 23762661; PubMed Central PMCID: PMC3665250.

11: Keller BO, Esbata AA, Buncel E, van Loon GW. Rapidly formed quinalphos complexes with transition metal ions characterized by electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom. 2013 Jun 30;27(12):1319-28. doi: 10.1002/rcm.6570. PubMed PMID: 23681809.

12: Mohammod Mostakim G, Zahangir MM, Monir Mishu M, Rahman MK, Islam MS. Alteration of Blood Parameters and Histoarchitecture of Liver and Kidney of Silver Barb after Chronic Exposure to Quinalphos. J Toxicol. 2015;2015:415984. doi: 10.1155/2015/415984. Epub 2015 Oct 8. PubMed PMID: 26635877; PubMed Central PMCID: PMC4618109.

13: Yashwanth B, Pamanji R, Rao JV. Toxicomorphomics and toxicokinetics of quinalphos on embryonic development of zebrafish (Danio rerio) and its binding affinity towards hatching enzyme, ZHE1. Aquat Toxicol. 2016 Nov;180:155-163. doi: 10.1016/j.aquatox.2016.09.018. Epub 2016 Oct 1. PubMed PMID: 27716580.

14: Pathan AR, Parihar NS, Sharma BN. Dissipation study of Quinalphos (25 EC) in/on brinjal and soil. Bull Environ Contam Toxicol. 2012 Jun;88(6):894-6. doi: 10.1007/s00128-012-0581-3. Epub 2012 Mar 22. PubMed PMID: 22437566.

15: Sadiqul IM, Ferdous Z, Nannu MTA, Mostakim GM, Rahman MK. Acute exposure to a quinalphos containing insecticide (convoy) causes genetic damage and nuclear changes in peripheral erythrocytes of silver barb, Barbonymus gonionotus. Environ Pollut. 2016 Dec;219:949-956. doi: 10.1016/j.envpol.2016.09.066. Epub 2016 Sep 22. PubMed PMID: 27667680.

16: Mohapatra S, Deepa M, Jagdish GK. Residue dynamics of tebuconazole and quinalphos in immature onion bulb with leaves, mature onion bulb and soil. Bull Environ Contam Toxicol. 2011 Dec;87(6):703-7. doi: 10.1007/s00128-011-0403-z. Epub 2011 Sep 16. PubMed PMID: 21922282.

17: Raizada RB, Srivastava MK, Singh RP, Kaushal RA, Gupta KP, Dikshith TS. Acute and subchronic oral toxicity of technical quinalphos in rats. Vet Hum Toxicol. 1993 Jun;35(3):223-5. PubMed PMID: 8351793.

18: Shukla Y, Singh A, Mehrotra NK. Evaluation of carcinogenic and co-carcinogenic potential Quinalphos in mouse skin. Cancer Lett. 2000 Jan 1;148(1):1-7. PubMed PMID: 10680586.

19: Gupta B, Rani M, Kumar R, Dureja P. Decay profile and metabolic pathways of quinalphos in water, soil and plants. Chemosphere. 2011 Oct;85(5):710-6. doi: 10.1016/j.chemosphere.2011.05.059. Epub 2011 Jun 25. PubMed PMID: 21708396.

20: Ray A, Chatterjee S, Bagchi P, Das TK, Deb C. Effect of quinalphos on testicular steroidogenesis in rats. Andrologia. 1988 Mar-Apr;20(2):163-8. PubMed PMID: 3164589.