GA3-AM
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Hodoodo CAT#: H563733

CAS#: 1373154-68-7

Description: GA3-AM is a cell permeable chemical dimerizer.


Chemical Structure

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GA3-AM
CAS# 1373154-68-7

Theoretical Analysis

Hodoodo Cat#: H563733
Name: GA3-AM
CAS#: 1373154-68-7
Chemical Formula: C23H28O7
Exact Mass: 416.18
Molecular Weight: 416.470
Elemental Analysis: C, 66.33; H, 6.78; O, 26.89

Price and Availability

Size Price Availability Quantity
10mg USD 240
50mg USD 530
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Synonym: GA3-AM; GA3 AM; GA3AM;

IUPAC/Chemical Name: acetoxymethyl (1S,2S,4aS,7S,9aS,10S)-2,7-dihydroxy-1-methyl-8-methylene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-1,4a-ethano-7,9a-methanobenzo[a]azulene-10-carboxylate

InChi Key: SEQNRAWXEHHXPO-WGQVIOJYSA-N

InChi Code: InChI=1S/C23H28O7/c1-12-8-22-10-23(12,28)7-4-14(22)21-6-5-15(25)20(3,16(26)9-21)18(21)17(22)19(27)30-11-29-13(2)24/h5-6,14-15,17-18,25,28H,1,4,7-11H2,2-3H3/t14?,15-,17+,18?,20-,21+,22-,23-/m0/s1

SMILES Code: O[C@]12C[C@](CC2=C)([C@H](C3[C@]4([C@H](C=C[C@]35CC4=O)O)C)C(OCOC(C)=O)=O)C5CC1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 416.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Wilmington SR, Matouschek A. An Inducible System for Rapid Degradation of Specific Cellular Proteins Using Proteasome Adaptors. PLoS One. 2016 Apr 4;11(4):e0152679. doi: 10.1371/journal.pone.0152679. eCollection 2016. PubMed PMID: 27043013; PubMed Central PMCID: PMC4820223.