Valencene
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    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H341379

CAS#: 4630-07-3

Description: Valencene is a sesquiterpene that is an aroma component of citrus fruit and citrus-derived odorants.

Chemical Structure

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Valencene
CAS# 4630-07-3
Instruction

Theoretical Analysis

Hodoodo Cat#: H341379
Name: Valencene
CAS#: 4630-07-3
Chemical Formula: C15H24
Exact Mass: 204.19
Molecular Weight: 204.357
Elemental Analysis: C, 88.16; H, 11.84

Price and Availability

Size Price Availability Quantity
1g USD 215 2 Weeks
5g USD 650 2 Weeks
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Synonym: Valencene; NSC 148969; NSC-148969; NSC148969.

IUPAC/Chemical Name: Naphthalene, 1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-, (1R,7R,8aS)-

InChi Key: QEBNYNLSCGVZOH-NFAWXSAZSA-N

InChi Code: InChI=1S/C15H24/c1-11(2)13-8-9-14-7-5-6-12(3)15(14,4)10-13/h7,12-13H,1,5-6,8-10H2,2-4H3/t12-,13-,15+/m1/s1

SMILES Code: C=C([C@@H]1CCC2=CCC[C@@H](C)[C@]2(C)C1)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 204.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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7: Kolwek J, Behrens C, Linke D, Krings U, Berger RG. Cell-free one-pot conversion of (+)-valencene to (+)-nootkatone by a unique dye-decolorizing peroxidase combined with a laccase from Funalia trogii. J Ind Microbiol Biotechnol. 2018 Feb;45(2):89-101. doi: 10.1007/s10295-017-1998-9. Epub 2017 Dec 22. PubMed PMID: 29270883.

8: Tisgratog R, Sukkanon C, Grieco JP, Sanguanpong U, Chauhan KR, Coats JR, Chareonviriyaphap T. Evaluation of the Constituents of Vetiver Oil Against Anopheles minimus (Diptera: Culicidae), a Malaria Vector in Thailand. J Med Entomol. 2018 Jan 10;55(1):193-199. doi: 10.1093/jme/tjx188. PubMed PMID: 29029183.

9: Alcoba AET, Melo DC, de Andrade PM, Dias HJ, Pagotti MC, Magalhães LG, Júnior WGF, Crotti AEM, Miranda MLD. Chemical composition and in vitro antileishmanial and cytotoxic activities of the essential oils of Ocotea dispersa (Nees) Mez and Ocotea odorifera (Vell) Rohwer (Lauraceae). Nat Prod Res. 2017 Oct 12:1-4. doi: 10.1080/14786419.2017.1385007. [Epub ahead of print] PubMed PMID: 29022353.

10: Ambrož M, Matoušková P, Skarka A, Zajdlová M, Žáková K, Skálová L. The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines. Molecules. 2017 Jun 20;22(6). pii: E1021. doi: 10.3390/molecules22061021. PubMed PMID: 28632185.

11: Zhang H, Xie Y, Liu C, Chen S, Hu S, Xie Z, Deng X, Xu J. Comprehensive comparative analysis of volatile compounds in citrus fruits of different species. Food Chem. 2017 Sep 1;230:316-326. doi: 10.1016/j.foodchem.2017.03.040. Epub 2017 Mar 10. PubMed PMID: 28407917.

12: Rahamooz Haghighi S, Asadi MH, Akrami H, Baghizadeh A. Anti-carcinogenic and anti-angiogenic properties of the extracts of Acorus calamus on gastric cancer cells. Avicenna J Phytomed. 2017 Mar-Apr;7(2):145-156. PubMed PMID: 28348970; PubMed Central PMCID: PMC5355820.

13: Silva DB, Weldegergis BT, Van Loon JJ, Bueno VH. Qualitative and Quantitative Differences in Herbivore-Induced Plant Volatile Blends from Tomato Plants Infested by Either Tuta absoluta or Bemisia tabaci. J Chem Ecol. 2017 Jan;43(1):53-65. doi: 10.1007/s10886-016-0807-7. Epub 2017 Jan 3. PubMed PMID: 28050733; PubMed Central PMCID: PMC5331093.

14: Yang IJ, Lee DU, Shin HM. Inhibitory Effect of Valencene on the Development of Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice. Evid Based Complement Alternat Med. 2016;2016:9370893. doi: 10.1155/2016/9370893. Epub 2016 Aug 18. PubMed PMID: 27630735; PubMed Central PMCID: PMC5007308.

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16: Mohadjerani M, Hosseinzadeh R, Hosseini M. Chemical composition and antibacterial properties of essential oil and fatty acids of different parts of Ligularia persica Boiss. Avicenna J Phytomed. 2016 May-Jun;6(3):357-65. PubMed PMID: 27462560; PubMed Central PMCID: PMC4930544.

17: Bazzali O, Thai TH, Hoi TM, Khang NS, Hien NT, Casanova J, Bighelli A, Tomi F. Integrated Analysis of the Wood Oil from Xanthocyparis vietnamensis Farjon & Hiep. by Chromatographic and Spectroscopic Techniques. Molecules. 2016 Jun 27;21(7). pii: E840. doi: 10.3390/molecules21070840. PubMed PMID: 27355937.

18: Federman C, Ma C, Biswas D. Major components of orange oil inhibit Staphylococcus aureus growth and biofilm formation, and alter its virulence factors. J Med Microbiol. 2016 Jul;65(7):688-95. doi: 10.1099/jmm.0.000286. Epub 2016 Jun 3. PubMed PMID: 27259704.

19: Shen SL, Yin XR, Zhang B, Xie XL, Jiang Q, Grierson D, Chen KS. CitAP2.10 activation of the terpene synthase CsTPS1 is associated with the synthesis of (+)-valencene in 'Newhall' orange. J Exp Bot. 2016 Jul;67(14):4105-15. doi: 10.1093/jxb/erw189. Epub 2016 May 18. PubMed PMID: 27194737; PubMed Central PMCID: PMC5301923.

20: Nam JH, Nam DY, Lee DU. Valencene from the Rhizomes of Cyperus rotundus Inhibits Skin Photoaging-Related Ion Channels and UV-Induced Melanogenesis in B16F10 Melanoma Cells. J Nat Prod. 2016 Apr 22;79(4):1091-6. doi: 10.1021/acs.jnatprod.5b01127. Epub 2016 Mar 11. PubMed PMID: 26967731.