WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H564026
CAS#: 1805787-93-2
Description: JAK3-IN-1 is a potent and selective JAK3 inhibitor.
Hodoodo Cat#: H564026
Name: JAK3-IN-1
CAS#: 1805787-93-2
Chemical Formula: C26H30ClN7O2
Exact Mass: 507.22
Molecular Weight: 508.020
Elemental Analysis: C, 61.47; H, 5.95; Cl, 6.98; N, 19.30; O, 6.30
Synonym: JAK3-IN-1; JAK3IN1; JAK3 IN 1; JAK3IN-1; JAK3-IN1
IUPAC/Chemical Name: N-[3-[[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]methyl]phenyl]-2-propenamide
InChi Key: UGXCBYVBIJACEK-UHFFFAOYSA-N
InChi Code: InChI=1S/C26H30ClN7O2/c1-4-24(35)30-19-7-5-6-18(14-19)16-28-25-21(27)17-29-26(32-25)31-22-9-8-20(15-23(22)36-3)34-12-10-33(2)11-13-34/h4-9,14-15,17H,1,10-13,16H2,2-3H3,(H,30,35)(H2,28,29,31,32)
SMILES Code: C=CC(NC1=CC=CC(CNC2=NC(NC3=CC=C(N4CCN(C)CC4)C=C3OC)=NC=C2Cl)=C1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
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The following data is based on the product molecular weight 508.02 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |