UCN-02
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Hodoodo CAT#: H564792

CAS#: 121569-61-7

Description: UCN-02 is a stereoisomer of UCN-01 which inhibits protein kinase C with a slightly reduced potency than UCN-01.

Chemical Structure

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UCN-02
CAS# 121569-61-7
Instruction

Theoretical Analysis

Hodoodo Cat#: H564792
Name: UCN-02
CAS#: 121569-61-7
Chemical Formula: C28H26N4O4
Exact Mass: 482.20
Molecular Weight: 482.540
Elemental Analysis: C, 69.70; H, 5.43; N, 11.61; O, 13.26

Price and Availability

Size Price Availability Quantity
1mg USD 520 2 Weeks
5mg USD 1650 2 Weeks
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Synonym: UCN02; UCN 02; UCN-02

IUPAC/Chemical Name: 18-Hydroxy-3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one

InChi Key: PBCZSGKMGDDXIJ-NXNPIKFHSA-N

InChi Code: InChI=1S/C28H26N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,27,29,34H,12H2,1-3H3,(H,30,33)/t15-,18-,25-,27?,28+/m0/s1

SMILES Code: O=C1C(C2=C3C4=C5C6=C(N4[C@@]7(C)[C@@H](OC)[C@@H](NC)C[C@@](O7)([H])N3C8=C2C=CC=C8)C=CC=C6)=C5C(O)N1

Appearance: A solution in ethanol

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 482.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Takahashi I, Asano K, Kawamoto I, Tamaoki T, Nakano H. UCN-01 and UCN-02, new selective inhibitors of protein kinase C. I. Screening, producing organism and fermentation. J Antibiot (Tokyo). 1989 Apr;42(4):564-70. PubMed PMID: 2722672.

2: Takahashi I, Saitoh Y, Yoshida M, Sano H, Nakano H, Morimoto M, Tamaoki T. UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II. Purification, physico-chemical properties, structural determination and biological activities. J Antibiot (Tokyo). 1989 Apr;42(4):571-6. PubMed PMID: 2656615.