AL-6556

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H573639

CAS#: 170552-18-8

Description: AL-6556 is a prostaglandin DP receptor agonist.

Chemical Structure

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AL-6556
CAS# 170552-18-8
Instruction

Theoretical Analysis

Hodoodo Cat#: H573639
Name: AL-6556
CAS#: 170552-18-8
Chemical Formula: C20H33ClO5
Exact Mass: 388.20
Molecular Weight: 388.930
Elemental Analysis: C, 61.76; H, 8.55; Cl, 9.11; O, 20.57

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: AL-6556, AL6556, AL 6556

IUPAC/Chemical Name: Acetic acid, 2-(((2Z)-4-((1R,2R,3R,5R)-5-chloro-2-((3R)-3-cyclohexyl-3-hydroxypropyl)-3-hydroxycyclopentyl)-2-buten-1-yl)oxy)-

InChi Key: WSKYUCGYZSXRPF-HOEVUQABSA-N

InChi Code: 1S/C20H33ClO5/c21-17-12-19(23)16(9-10-18(22)14-6-2-1-3-7-14)15(17)8-4-5-11-26-13-20(24)25/h4-5,14-19,22-23H,1-3,6-13H2,(H,24,25)/b5-4-/t15-,16-,17-,18-,19-/m1/s1

SMILES Code: O[C@H](CC[C@H]1[C@H](O)C[C@@H](Cl)[C@@H]1C\C=C/COCC(=O)O)C2CCCCC2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 388.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Sharif NA, Davis TL, Williams GW. Ocular hypotensive DP-class prostaglandin receptor affinities determined by quantitative autoradiography on human eye sections. J Ocul Pharmacol Ther. 2005 Apr;21(2):121-32. PubMed PMID: 15857278.

2: Sharif NA, Williams GW, Crider JY, Xu SX, Davis TL. Molecular pharmacology of the DP/EP2 class prostaglandin AL-6598 and quantitative autoradiographic visualization of DP and EP2 receptor sites in human eyes. J Ocul Pharmacol Ther. 2004 Dec;20(6):489-508. PubMed PMID: 15684809.

3: Hellberg MR, Conrow RE, Sharif NA, McLaughlin MA, Bishop JE, Crider JY, Dean WD, DeWolf KA, Pierce DR, Sallee VL, Selliah RD, Severns BS, Sproull SJ, Williams GW, Zinke PW, Klimko PG. 3-Oxa-15-cyclohexyl prostaglandin DP receptor agonists as topical antiglaucoma agents. Bioorg Med Chem. 2002 Jun;10(6):2031-49. PubMed PMID: 11937363.