CPX

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H565603

CAS#: N/A

Description: CPX is a novel "clickable" photoconvertible fluorescent minimalist probe for tracking individual biomolecule complexes

Chemical Structure

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CPX
CAS# N/A
Instruction

Theoretical Analysis

Hodoodo Cat#: H565603
Name: CPX
CAS#: N/A
Chemical Formula: C32H26F3N5O4
Exact Mass: 601.19
Molecular Weight: 601.586
Elemental Analysis: C, 63.89; H, 4.36; F, 9.47; N, 11.64; O, 10.64

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: CPX

IUPAC/Chemical Name: (Z)-1-(6-Azidohexyl)-[10,10'-bichromeno[3,2-b]pyridinylidene]-1-ium trifluoroacetate

InChi Key: FHQZADYMZZYPMI-LXCLTORNSA-M

InChi Code: InChI=1S/C30H26N5O2.C2HF3O2/c31-34-33-18-7-1-2-8-19-35-20-10-16-26-30(35)28(22-12-4-6-14-24(22)37-26)27-21-11-3-5-13-23(21)36-25-15-9-17-32-29(25)27;3-2(4,5)1(6)7/h3-6,9-17,20H,1-2,7-8,18-19H2;(H,6,7)/q+1;/p-1/b28-27-;

SMILES Code: [N-]=[N+]=NCCCCCC[N+]1=CC=CC2=C1/C(C3=C(O2)C=CC=C3)=C(C4=NC=CC=C4O5)/C6=C5C=CC=C6.O=C([O-])C(F)(F)F

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 601.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Imboden MT, Harber MP, Whaley MH, Finch WH, Bishop DA, Fleenor BS, Kaminsky LA. The Influence of Change in Cardiorespiratory Fitness With Short-Term Exercise Training on Mortality Risk From The Ball State Adult Fitness Longitudinal Lifestyle Study. Mayo Clin Proc. 2019 Jul 11. pii: S0025-6196(19)30254-X. doi: 10.1016/j.mayocp.2019.01.049. [Epub ahead of print] PubMed PMID: 31303425.

2: Kam BS, Yune SJ, Lee SY, Im SJ, Baek SY. Impact of video feedback system on medical students' perception of their clinical performance assessment. BMC Med Educ. 2019 Jul 8;19(1):252. doi: 10.1186/s12909-019-1688-6. PubMed PMID: 31286961; PubMed Central PMCID: PMC6615181.

3: Thapa M, Singh M, Ghosh CK, Biswas PK, Mukherjee A. Zinc sulphide nanoparticle (nZnS): A novel nano-modulator for plant growth. Plant Physiol Biochem. 2019 Jun 26;142:73-83. doi: 10.1016/j.plaphy.2019.06.031. [Epub ahead of print] PubMed PMID: 31277044.

4: Nakade T, Adachi H, Murata M, Oshima S. Relationship Between Exercise Oscillatory Ventilation Loop and Prognosis of Heart Failure. Circ J. 2019 Jul 25;83(8):1718-1725. doi: 10.1253/circj.CJ-18-1047. Epub 2019 Jun 28. PubMed PMID: 31257356.

5: Alemán-Campos Y, Kourí-Cordellá V, Pérez-Santos L, Fonseca-Gómez C, Pérez-Ávila J, Ortega-González LM, Baños-Morales Y, Álvarez-López A, Correa-Sierra CB, Martínez-Montesinos Y, Soto-Brito Y, Limia-León CM, Campos-Díaz JR, Caturla-Fernández Y, Alvarez-Gainza D, Pintos-Saavedra Y, Añé-Kourí AL, Joanes-Fiol J. HIV-1 Antiretroviral Resistance in Cuba, 2009-2014. MEDICC Rev. 2018 Jul;20(3):15-21. PubMed PMID: 31242157.

6: Mayer LD, Tardi P, Louie AC. CPX-351: a nanoscale liposomal co-formulation of daunorubicin and cytarabine with unique biodistribution and tumor cell uptake properties. Int J Nanomedicine. 2019 May 23;14:3819-3830. doi: 10.2147/IJN.S139450. eCollection 2019. Review. PubMed PMID: 31213803; PubMed Central PMCID: PMC6537039.

7: Maakaron JE, Mims AS. Daunorubicin-cytarabine liposome (CPX-351) in the management of newly diagnosed secondary AML: A new twist on an old cocktail. Best Pract Res Clin Haematol. 2019 Jun;32(2):127-133. doi: 10.1016/j.beha.2019.05.005. Epub 2019 May 13. Review. PubMed PMID: 31203994.

8: Beamud B, Bracho MA, González-Candelas F. Characterization of New Recombinant Forms of HIV-1 From the Comunitat Valenciana (Spain) by Phylogenetic Incongruence. Front Microbiol. 2019 May 22;10:1006. doi: 10.3389/fmicb.2019.01006. eCollection 2019. PubMed PMID: 31191463; PubMed Central PMCID: PMC6540936.

9: Lierenfeld MB, Zhong X, Reusser E, Kunze K, Putlitz B, Ulmer P. Species diffusion in clinopyroxene solid solution in the diopside-anorthite system. Contrib Mineral Petrol. 2019;174(5):46. doi: 10.1007/s00410-019-1571-9. Epub 2019 May 13. PubMed PMID: 31178597; PubMed Central PMCID: PMC6515693.

10: Bertoli S, Tavitian S, Bories P, Luquet I, Delabesse E, Comont T, Sarry A, Huguet F, Bérard E, Récher C. Outcome of patients aged 60-75 years with newly diagnosed secondary acute myeloid leukemia: A single-institution experience. Cancer Med. 2019 Jul;8(8):3846-3854. doi: 10.1002/cam4.2020. Epub 2019 Jun 7. PubMed PMID: 31173485.

11: Tidhar A, Levy Y, Zauberman A, Vagima Y, Gur D, Aftalion M, Israeli O, Chitlaru T, Ariel N, Flashner Y, Zvi A, Mamroud E. Disruption of the NlpD lipoprotein of the plague pathogen Yersinia pestis affects iron acquisition and the activity of the twin-arginine translocation system. PLoS Negl Trop Dis. 2019 Jun 6;13(6):e0007449. doi: 10.1371/journal.pntd.0007449. eCollection 2019 Jun. PubMed PMID: 31170147; PubMed Central PMCID: PMC6553720.

12: Soodla P, Huik K, Pauskar M, Cuypers L, Van Laethem K, Rajasaar H, Kallas E, Lepa H, Velts-Lindh A, Jõgeda EL, Lutsar I, Avi R. Stable level of HIV transmitted drug resistance in Estonia despite significant scale-up of antiretroviral therapy. Infect Genet Evol. 2019 May 28:103901. doi: 10.1016/j.meegid.2019.05.019. [Epub ahead of print] PubMed PMID: 31146045.

13: Nakanishi M, Miura H, Nakao K, Fujino M, Arakawa T, Fukui S, Hasegawa T, Yanase M, Noguchi T, Goto Y, Yasuda S. Combination of Peak Exercise Systolic Blood Pressure and Left Atrial Diameter as a Novel Non-Spirometry Prognostic Predictor Comparable to Peak Oxygen Uptake for Heart Failure With Reduced Ejection Fraction. Circ J. 2019 Jun 25;83(7):1528-1537. doi: 10.1253/circj.CJ-18-1111. Epub 2019 May 30. PubMed PMID: 31142704.

14: Leung KS, To SW, Chen JH, Siu GK, Chan KC, Yam WC. Molecular Characterization of HIV-1 Minority Subtypes in Hong Kong: A Recent Epidemic of CRF07_BC among the Men who have Sex with Men Population. Curr HIV Res. 2019;17(1):53-64. doi: 10.2174/1570162X17666190530081355. PubMed PMID: 31142258.

15: May KL, Lehman KM, Mitchell AM, Grabowicz M. A Stress Response Monitoring Lipoprotein Trafficking to the Outer Membrane. MBio. 2019 May 28;10(3). pii: e00618-19. doi: 10.1128/mBio.00618-19. PubMed PMID: 31138744; PubMed Central PMCID: PMC6538781.

16: Economides MP, McCue D, Borthakur G, Pemmaraju N. Topoisomerase II inhibitors in AML: past, present, and future. Expert Opin Pharmacother. 2019 May 28:1-8. doi: 10.1080/14656566.2019.1621292. [Epub ahead of print] PubMed PMID: 31136213.

17: Yi Z, Wang D, Xin S, Zhou D, Li T, Tian M, Qi J, Ding C, Wang S, Yu S. The CpxR regulates type VI secretion system 2 expression and facilitates the interbacterial competition activity and virulence of avian pathogenic Escherichia coli. Vet Res. 2019 May 24;50(1):40. doi: 10.1186/s13567-019-0658-7. PubMed PMID: 31126325; PubMed Central PMCID: PMC6534853.

18: Huik K, Soodla P, Pauskar M, Owen SM, Luo W, Murphy G, Jõgeda EL, Kallas E, Rajasaar H, Avi R, Masciotra S, Lutsar I; CASCADE Collaboration in the EuroCoord. The concordance of the limiting antigen and the Bio-Rad avidity assays in persons from Estonia infected mainly with HIV-1 CRF06_cpx. PLoS One. 2019 May 24;14(5):e0217048. doi: 10.1371/journal.pone.0217048. eCollection 2019. PubMed PMID: 31125356; PubMed Central PMCID: PMC6534295.

19: Liu X, He X, Zhang X, Wang Y, Liu J, Hao X, Zhang Y, Yuan XA, Tian L, Liu Z. Synthesis and Antineoplastic Applications of TPE Appended Organometallic Iridium(III) Complexes. Chembiochem. 2019 May 21. doi: 10.1002/cbic.201900268. [Epub ahead of print] PubMed PMID: 31119850.

20: Weir SJ, Wood R, Schorno K, Brinker AE, Ramamoorthy P, Heppert K, Rajewski L, Tanol M, Ham T, McKenna MJ, McCulloch W, Dalton M, Reed GA, Jensen RA, Baltezor MJ, Anant S, Taylor JA 3rd. Preclinical Pharmacokinetics of Fosciclopirox, a Novel Treatment of Urothelial Cancers, in Rats and Dogs. J Pharmacol Exp Ther. 2019 Aug;370(2):148-159. doi: 10.1124/jpet.119.257972. Epub 2019 May 21. PubMed PMID: 31113837; PubMed Central PMCID: PMC6614794.