WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H532980
CAS#: 287177-12-2
Description: F1386-0303 is a novel potent and selective MAP4K4 inhibitor.
Hodoodo Cat#: H532980
Name: F1386-0303
CAS#: 287177-12-2
Chemical Formula: C18H13N3O
Exact Mass: 287.11
Molecular Weight: 287.322
Elemental Analysis: C, 75.25; H, 4.56; N, 14.63; O, 5.57
This product is not in stock, which may be available by custom synthesis.
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Synonym: F1386-0303; F1386 0303; F13860303
IUPAC/Chemical Name: 5,7-Diphenyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
InChi Key: YTLWLZPZXNOVGS-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H13N3O/c22-18-16-15(13-7-3-1-4-8-13)11-21(17(16)19-12-20-18)14-9-5-2-6-10-14/h1-12H,(H,19,20,22)
SMILES Code: O=C1C2=C(N(C3=CC=CC=C3)C=C2C4=CC=CC=C4)N=CN1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
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The following data is based on the product molecular weight 287.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |