Nepodin
new
featured

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H471034

CAS#: 3785-24-8

Description: Nepodin, also know as Musizin; is a naphthol that has been found in Rumex and has diverse biological activities

Chemical Structure

img
Nepodin
CAS# 3785-24-8
Instruction

Theoretical Analysis

Hodoodo Cat#: H471034
Name: Nepodin
CAS#: 3785-24-8
Chemical Formula: C13H12O3
Exact Mass: 216.08
Molecular Weight: 216.236
Elemental Analysis: C, 72.21; H, 5.59; O, 22.20

Price and Availability

Size Price Availability Quantity
5mg USD 310 2 Weeks
10mg USD 410 2 Weeks
Bulk inquiry

Synonym: Nepodin, Musizin; NSC 365795; NSC365795; NSC-365795

IUPAC/Chemical Name: 1-(1,8-dihydroxy-3-methyl-2-naphthalenyl)-ethanone

InChi Key: DMLHPCALHMPJHS-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H12O3/c1-7-6-9-4-3-5-10(15)12(9)13(16)11(7)8(2)14/h3-6,15-16H,1-2H3

SMILES Code: CC(C1=C(C)C=C2C=CC=C(O)C2=C1O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 216.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1. Lee, J.H., Kim, Y.G., Khadke, S.K., et al. Inhibition of biofilm formation by Candida albicans and polymicrobial microorganisms by nepodin via hyphal-growth suppression. ACS Infect. Dis. 5(7), 1177-1187 (2019).

2. Grover, J., Kumar, V., Singh, V., et al. Synthesis, biological evaluation, molecular docking and theoretical evaluation of ADMET properties of nepodin and chrysophanol derivatives as potential cyclooxygenase (COX-1, COX-2) inhibitors. Eur. J. Med. Chem. 80, 47-56 (2014)

3. Ha, B.G., Yonezawa, T., Son, M.J., et al. Antidiabetic effect of nepodin, a component of Rumex roots, and its modes of action in vitro and in vivo. Biofactors 40(4), 436-447 (2014).

4. Lee, K.H., and Rhee, K.H. Antimalarial activity of nepodin isolated from Rumex crispus. Arch. Pharm. Res. 36(4), 430-435 (2013)