WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H585451
CAS#: 105568-35-2
Description: Y 19995 is a synthetic compound affecting the host defense in immuno-compromised mice.
Hodoodo Cat#: H585451
Name: Y 19995
CAS#: 105568-35-2
Chemical Formula: C30H39N3O11
Exact Mass: 617.26
Molecular Weight: 617.652
Elemental Analysis: C, 58.34; H, 6.36; N, 6.80; O, 28.49
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Synonym: Y 19995; Y19995; Y-19995
IUPAC/Chemical Name: Methanone, (4-(2-(dimethylamino)-1-methylethoxy)phenyl)(2-(2-(dimethylamino)-1-methylethoxy)-3-pyridinyl)-, (Z)-2-butenedioate (1:2)
InChi Key: ZOXYGRVFSDRYOS-SPIKMXEPSA-N
InChi Code: InChI=1S/C22H31N3O3.2C4H4O4/c1-16(14-24(3)4)27-19-11-9-18(10-12-19)21(26)20-8-7-13-23-22(20)28-17(2)15-25(5)6;2*5-3(6)1-2-4(7)8/h7-13,16-17H,14-15H2,1-6H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
SMILES Code: O=C(C1=CC=C(OC(C)CN(C)C)C=C1)C2=CC=CN=C2OC(C)CN(C)C.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 617.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Tsuru S, Shinomiya N, Nomoto K. Depression of early protection against influenza virus infection by cyclophosphamide and its restoration by Y-19995 [2,4'-bis(1-methyl-2-dimethyl-aminoethoxyl)-3-benzoylpyridine dimaleate]. Nat Immun Cell Growth Regul. 1991;10(1):1-11. PubMed PMID: 2057018.
2: Fujisawa H, Tsuru S, Taniguchi M, Nomoto K. Enhancement of host defence by Y-19995 (2,4'-bis(1-methyl-2-dimethyl-aminoethoxyl)-3-benzoylpyridine dimaleate), a novel synthetic compound. II. Activation of phagocytic cell functions. J Clin Lab Immunol. 1987 Dec;24(4):177-81. PubMed PMID: 3502347.
3: Fujisawa H, Tsuru S, Hisatome M, Goto K, Oe T, Okumoto T, Taniguchi M, Nomoto K. Enhancement of host defence by Y-19995 (2,4'-bis(1-methyl-2-dimethyl-aminoethoxyl)-3-benzoylpyridine dimaleate), a novel synthetic compound. I. Accelerated restoration from the leukocytopenia and augmented protection against microbial infections in immunocompromised mice. J Clin Lab Immunol. 1987 Aug;23(4):203-8. PubMed PMID: 3312612.