N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H462147

CAS#: 2380261-53-8

Description: N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide is an inhibitor of hypoxia-inducible factor (HIF-1) signaling.


Chemical Structure

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N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide
CAS# 2380261-53-8

Theoretical Analysis

Hodoodo Cat#: H462147
Name: N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide
CAS#: 2380261-53-8
Chemical Formula: C21H19FN2O2
Exact Mass: 350.14
Molecular Weight: 350.393
Elemental Analysis: C, 71.99; H, 5.47; F, 5.42; N, 8.00; O, 9.13

Price and Availability

Size Price Availability Quantity
1mg USD 245 2 Weeks
5mg USD 566 2 Weeks
10mg USD 873 2 Weeks
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Synonym: N-(2-Fluorophenethyl)-5-(2-methoxyphenyl)picolinamide

IUPAC/Chemical Name: N-[2-(2-fluorophenyl)ethyl]-5-(2-methoxyphenyl)-2-pyridinecarboxamide

InChi Key: JZEJSNMITKBPGZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H19FN2O2/c1-26-20-9-5-3-7-17(20)16-10-11-19(24-14-16)21(25)23-13-12-15-6-2-4-8-18(15)22/h2-11,14H,12-13H2,1H3,(H,23,25)

SMILES Code: COC1=CC=CC=C1C2=CN=C(C(NCCC3=CC=CC=C3F)=O)C=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 350.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Liu, M., Liang, Y., Zhu, Z., et al. Discovery of novel aryl carboxamide derivatives as hypoxia-inducible factor 1α signaling inhibitors with potent activities of anticancer metastasis. J. Med. Chem. 62(20), 9299-9314 (2019).