WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H462223
CAS#: 890402-73-0
Description: XP-59 is a potent inhibitor of the SARS-CoV Mpro
Hodoodo Cat#: H462223
Name: XP-59
CAS#: 890402-73-0
Chemical Formula: C15H14N4O2
Exact Mass: 282.11
Molecular Weight: 282.303
Elemental Analysis: C, 63.82; H, 5.00; N, 19.85; O, 11.33
Synonym: XP-59; XP 59; XP59;
IUPAC/Chemical Name: 1H-benzo[d][1,2,3]triazol-1-yl 4-(dimethylamino)benzoate
InChi Key: UOITWBIZHQLMTH-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H14N4O2/c1-18(2)12-9-7-11(8-10-12)15(20)21-19-14-6-4-3-5-13(14)16-17-19/h3-10H,1-2H3
SMILES Code: O=C(ON1N=NC2=CC=CC=C21)C3=CC=C(N(C)C)C=C3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 282.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Verschueren KH, Pumpor K, Anemüller S, Chen S, Mesters JR, Hilgenfeld R. A structural view of the inactivation of the SARS coronavirus main proteinase by benzotriazole esters. Chem Biol. 2008;15(6):597-606. doi:10.1016/j.chembiol.2008.04.011